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Proteome Stability as a Key Factor of Genome Integrity.
Gumeni S, Evangelakou Z, Gorgoulis VG, Trougakos IP. Gumeni S, et al. Among authors: trougakos ip. Int J Mol Sci. 2017 Sep 22;18(10):2036. doi: 10.3390/ijms18102036. Int J Mol Sci. 2017. PMID: 28937603 Free PMC article. Review.
A prototypical non-malignant epithelial model to study genome dynamics and concurrently monitor micro-RNAs and proteins in situ during oncogene-induced senescence.
Komseli ES, Pateras IS, Krejsgaard T, Stawiski K, Rizou SV, Polyzos A, Roumelioti FM, Chiourea M, Mourkioti I, Paparouna E, Zampetidis CP, Gumeni S, Trougakos IP, Pefani DE, O'Neill E, Gagos S, Eliopoulos AG, Fendler W, Chowdhury D, Bartek J, Gorgoulis VG. Komseli ES, et al. Among authors: trougakos ip. BMC Genomics. 2018 Jan 10;19(1):37. doi: 10.1186/s12864-017-4375-1. BMC Genomics. 2018. PMID: 29321003 Free PMC article.
Proteasome dysfunction induces excessive proteome instability and loss of mitostasis that can be mitigated by enhancing mitochondrial fusion or autophagy.
Tsakiri EN, Gumeni S, Vougas K, Pendin D, Papassideri I, Daga A, Gorgoulis V, Juhász G, Scorrano L, Trougakos IP. Tsakiri EN, et al. Among authors: trougakos ip. Autophagy. 2019 Oct;15(10):1757-1773. doi: 10.1080/15548627.2019.1596477. Epub 2019 Apr 19. Autophagy. 2019. PMID: 31002009 Free PMC article.
193 results