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Therapeutic Inhibition of the Receptor Tyrosine Kinase AXL Improves Sensitivity to Platinum and Taxane in Ovarian Cancer.
Quinn JM, Greenwade MM, Palisoul ML, Opara G, Massad K, Guo L, Zhao P, Beck-Noia H, Hagemann IS, Hagemann AR, McCourt CK, Thaker PH, Powell MA, Mutch DG, Fuh KC. Quinn JM, et al. Among authors: fuh kc. Mol Cancer Ther. 2019 Feb;18(2):389-398. doi: 10.1158/1535-7163.MCT-18-0537. Epub 2018 Nov 26. Mol Cancer Ther. 2019. PMID: 30478151 Free PMC article.
GAS6/AXL Inhibition Enhances Ovarian Cancer Sensitivity to Chemotherapy and PARP Inhibition through Increased DNA Damage and Enhanced Replication Stress.
Mullen MM, Lomonosova E, Toboni MD, Oplt A, Cybulla E, Blachut B, Zhao P, Noia H, Wilke D, Rankin EB, Kuroki LM, Hagemann AR, Hagemann IS, McCourt CK, Thaker PH, Mutch DG, Powell MA, Mosammaparast N, Vindigni A, Fuh KC. Mullen MM, et al. Among authors: fuh kc. Mol Cancer Res. 2022 Feb;20(2):265-279. doi: 10.1158/1541-7786.MCR-21-0302. Epub 2021 Oct 20. Mol Cancer Res. 2022. PMID: 34670865 Free PMC article.
GAS6-AXL Inhibition by AVB-500 Overcomes Resistance to Paclitaxel in Endometrial Cancer by Decreasing Tumor Cell Glycolysis.
Bruce SF, Cho K, Noia H, Lomonosova E, Stock EC, Oplt A, Blachut B, Mullen MM, Kuroki LM, Hagemann AR, McCourt CK, Thaker PH, Khabele D, Powell MA, Mutch DG, Shriver LP, Patti GJ, Fuh KC. Bruce SF, et al. Among authors: fuh kc. Mol Cancer Ther. 2022 Aug 2;21(8):1348-1359. doi: 10.1158/1535-7163.MCT-21-0704. Mol Cancer Ther. 2022. PMID: 35588308 Free PMC article.
Genetic characterization of primary and metastatic high-grade serous ovarian cancer tumors reveals distinct features associated with survival.
Kotnik EN, Mullen MM, Spies NC, Li T, Inkman M, Zhang J, Martins-Rodrigues F, Hagemann IS, McCourt CK, Thaker PH, Hagemann AR, Powell MA, Mutch DG, Khabele D, Longmore GD, Mardis ER, Maher CA, Miller CA, Fuh KC. Kotnik EN, et al. Among authors: fuh kc. Commun Biol. 2023 Jul 3;6(1):688. doi: 10.1038/s42003-023-05026-3. Commun Biol. 2023. PMID: 37400526 Free PMC article.
Stromal DDR2 Promotes Ovarian Cancer Metastasis through Regulation of Metabolism and Secretion of Extracellular Matrix Proteins.
Schab AM, Greenwade MM, Stock E, Lomonosova E, Cho K, Grither WR, Noia H, Wilke D, Mullen MM, Hagemann AR, Hagemann IS, Thaker PH, Kuroki LM, McCourt CK, Khabele D, Powell MA, Mutch DG, Zhao P, Shriver LP, Patti GJ, Longmore GD, Fuh KC. Schab AM, et al. Among authors: fuh kc. Mol Cancer Res. 2023 Nov 1;21(11):1234-1248. doi: 10.1158/1541-7786.MCR-23-0347. Mol Cancer Res. 2023. PMID: 37527178 Free PMC article.
Collagen Remodeling in the Hypoxic Tumor-Mesothelial Niche Promotes Ovarian Cancer Metastasis.
Natarajan S, Foreman KM, Soriano MI, Rossen NS, Shehade H, Fregoso DR, Eggold JT, Krishnan V, Dorigo O, Krieg AJ, Heilshorn SC, Sinha S, Fuh KC, Rankin EB. Natarajan S, et al. Among authors: fuh kc. Cancer Res. 2019 May 1;79(9):2271-2284. doi: 10.1158/0008-5472.CAN-18-2616. Epub 2019 Mar 12. Cancer Res. 2019. PMID: 30862717 Free PMC article.
77 results