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Multifaceted immune dysregulation characterizes individuals at-risk for rheumatoid arthritis.
James EA, Holers VM, Iyer R, Prideaux EB, Rao NL, Rims C, Muir VS, Posso SE, Bloom MS, Zia A, Elliott SE, Adamska JZ, Ai R, Brewer RC, Seifert JA, Moss L, Barzideh S, Demoruelle MK, Striebich CC, Okamoto Y, Sainbayar E, Crook AA, Peterson RA, Vanderlinden LA, Wang W, Boyle DL, Robinson WH, Buckner JH, Firestein GS, Deane KD. James EA, et al. Among authors: wang w. Nat Commun. 2023 Nov 22;14(1):7637. doi: 10.1038/s41467-023-43091-8. Nat Commun. 2023. PMID: 37993439 Free PMC article.
DNA methylome signature in rheumatoid arthritis.
Nakano K, Whitaker JW, Boyle DL, Wang W, Firestein GS. Nakano K, et al. Among authors: wang w. Ann Rheum Dis. 2013 Jan;72(1):110-7. doi: 10.1136/annrheumdis-2012-201526. Epub 2012 Jun 26. Ann Rheum Dis. 2013. PMID: 22736089 Free PMC article.
Synoviocyte-targeted therapy synergizes with TNF inhibition in arthritis reversal.
Svensson MND, Zoccheddu M, Yang S, Nygaard G, Secchi C, Doody KM, Slowikowski K, Mizoguchi F, Humby F, Hands R, Santelli E, Sacchetti C, Wakabayashi K, Wu DJ, Barback C, Ai R, Wang W, Sims GP, Mydel P, Kasama T, Boyle DL, Galimi F, Vera D, Tremblay ML, Raychaudhuri S, Brenner MB, Firestein GS, Pitzalis C, Ekwall AH, Stanford SM, Bottini N. Svensson MND, et al. Among authors: wang w. Sci Adv. 2020 Jun 26;6(26):eaba4353. doi: 10.1126/sciadv.aba4353. eCollection 2020 Jun. Sci Adv. 2020. PMID: 32637608 Free PMC article.
Systems-biology analysis of rheumatoid arthritis fibroblast-like synoviocytes implicates cell line-specific transcription factor function.
Ainsworth RI, Hammaker D, Nygaard G, Ansalone C, Machado C, Zhang K, Zheng L, Carrillo L, Wildberg A, Kuhs A, Svensson MND, Boyle DL, Firestein GS, Wang W. Ainsworth RI, et al. Among authors: wang w. Nat Commun. 2022 Oct 20;13(1):6221. doi: 10.1038/s41467-022-33785-w. Nat Commun. 2022. PMID: 36266270 Free PMC article.
Enhancing KDM5A and TLR activity improves the response to immune checkpoint blockade.
Wang L, Gao Y, Zhang G, Li D, Wang Z, Zhang J, Hermida LC, He L, Wang Z, Si J, Geng S, Ai R, Ning F, Cheng C, Deng H, Dimitrov DS, Sun Y, Huang Y, Wang D, Hu X, Wei Z, Wang W, Liao X. Wang L, et al. Among authors: wang w, wang z, wang d. Sci Transl Med. 2020 Sep 9;12(560):eaax2282. doi: 10.1126/scitranslmed.aax2282. Sci Transl Med. 2020. PMID: 32908002
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