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Megakaryocytes possess a STING pathway that is transferred to platelets to potentiate activation.
El-Mortada F, Landelouci K, Bertrand-Perron S, Aubé FA, Poirier A, Bidias A, Jourdi G, Welman M, Gantier MP, Hamilton JR, Kile B, Lordkipanidzé M, Pépin G. El-Mortada F, et al. Among authors: hamilton jr. Life Sci Alliance. 2023 Nov 22;7(2):e202302211. doi: 10.26508/lsa.202302211. Print 2024 Feb. Life Sci Alliance. 2023. PMID: 37993259 Free PMC article.
Transgenic, inducible RNAi in megakaryocytes and platelets in mice.
Takiguchi M, James C, Josefsson EC, Carmichael CL, Premsrirut PK, Lowe SW, Hamilton JR, Huang DC, Kile BT, Dickins RA. Takiguchi M, et al. Among authors: hamilton jr. J Thromb Haemost. 2010 Dec;8(12):2751-6. doi: 10.1111/j.1538-7836.2010.04077.x. J Thromb Haemost. 2010. PMID: 21138522 Free PMC article.
Shared roles for Scl and Lyl1 in murine platelet production and function.
Chiu SK, Orive SL, Moon MJ, Saw J, Ellis S, Kile BT, Huang Y, Chacon D, Pimanda JE, Beck D, Hamilton JR, Tremblay CS, Curtis DJ. Chiu SK, et al. Among authors: hamilton jr. Blood. 2019 Sep 5;134(10):826-835. doi: 10.1182/blood.2019896175. Epub 2019 Jul 12. Blood. 2019. PMID: 31300405 Free article.
The class II PI 3-kinase, PI3KC2α, links platelet internal membrane structure to shear-dependent adhesive function.
Mountford JK, Petitjean C, Putra HW, McCafferty JA, Setiabakti NM, Lee H, Tønnesen LL, McFadyen JD, Schoenwaelder SM, Eckly A, Gachet C, Ellis S, Voss AK, Dickins RA, Hamilton JR, Jackson SP. Mountford JK, et al. Among authors: hamilton jr. Nat Commun. 2015 Mar 17;6:6535. doi: 10.1038/ncomms7535. Nat Commun. 2015. PMID: 25779105 Free article.
475 results