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Use of a biomimetic hydrogel depot technology for sustained delivery of GLP-1 receptor agonists reduces burden of diabetes management.
d'Aquino AI, Maikawa CL, Nguyen LT, Lu K, Hall IA, Jons CK, Kasse CM, Yan J, Prossnitz AN, Chang E, Baker SW, Hovgaard L, Steensgaard DB, Andersen HB, Simonsen L, Appel EA. d'Aquino AI, et al. Among authors: maikawa cl. Cell Rep Med. 2023 Nov 21;4(11):101292. doi: 10.1016/j.xcrm.2023.101292. Cell Rep Med. 2023. PMID: 37992687 Free PMC article.
Delivery of CAR-T cells in a transient injectable stimulatory hydrogel niche improves treatment of solid tumors.
Grosskopf AK, Labanieh L, Klysz DD, Roth GA, Xu P, Adebowale O, Gale EC, Jons CK, Klich JH, Yan J, Maikawa CL, Correa S, Ou BS, d'Aquino AI, Cochran JR, Chaudhuri O, Mackall CL, Appel EA. Grosskopf AK, et al. Among authors: maikawa cl. Sci Adv. 2022 Apr 8;8(14):eabn8264. doi: 10.1126/sciadv.abn8264. Epub 2022 Apr 8. Sci Adv. 2022. PMID: 35394838 Free PMC article.
A co-formulation of supramolecularly stabilized insulin and pramlintide enhances mealtime glucagon suppression in diabetic pigs.
Maikawa CL, Smith AAA, Zou L, Roth GA, Gale EC, Stapleton LM, Baker SW, Mann JL, Yu AC, Correa S, Grosskopf AK, Liong CS, Meis CM, Chan D, Troxell M, Maahs DM, Buckingham BA, Webber MJ, Appel EA. Maikawa CL, et al. Nat Biomed Eng. 2020 May;4(5):507-517. doi: 10.1038/s41551-020-0555-4. Epub 2020 May 11. Nat Biomed Eng. 2020. PMID: 32393892 Free PMC article.
Full closed loop open-source algorithm performance comparison in pigs with diabetes.
Lal RA, Maikawa CL, Lewis D, Baker SW, Smith AAA, Roth GA, Gale EC, Stapleton LM, Mann JL, Yu AC, Correa S, Grosskopf AK, Liong CS, Meis CM, Chan D, Garner JP, Maahs DM, Buckingham BA, Appel EA. Lal RA, et al. Among authors: maikawa cl. Clin Transl Med. 2021 Apr;11(4):e387. doi: 10.1002/ctm2.387. Clin Transl Med. 2021. PMID: 33931977 Free PMC article.
30 results