Choi SH - Search Results

1

Structure-Based Discovery of A Small Molecule Inhibitor of Histone Deacetylase 6 (HDAC6) that Significantly Reduces Alzheimer's Disease Neuropathology.

Mondal P, Bai P, Gomm A, Bakiasi G, Lin CJ, Wang Y, Choi SH, Tanzi RE, Wang C, Zhang C. Mondal P, et al. Among authors: choi sh. Adv Sci (Weinh). 2024 Jan;11(1):e2304545. doi: 10.1002/advs.202304545. Epub 2023 Nov 21. Adv Sci (Weinh). 2024. PMID: 37990786 Free PMC article.

2

Blood-Brain Barrier Dysfunction in a 3D In Vitro Model of Alzheimer's Disease.

Shin Y, Choi SH, Kim E, Bylykbashi E, Kim JA, Chung S, Kim DY, Kamm RD, Tanzi RE. Shin Y, et al. Among authors: choi sh. Adv Sci (Weinh). 2019 Aug 12;6(20):1900962. doi: 10.1002/advs.201900962. eCollection 2019 Oct 16. Adv Sci (Weinh). 2019. PMID: 31637161 Free PMC article.

3

Development of a potential PET probe for HDAC6 imaging in Alzheimer's disease.

Bai P, Mondal P, Bagdasarian FA, Rani N, Liu Y, Gomm A, Tocci DR, Choi SH, Wey HY, Tanzi RE, Zhang C, Wang C. Bai P, et al. Among authors: choi sh. Acta Pharm Sin B. 2022 Oct;12(10):3891-3904. doi: 10.1016/j.apsb.2022.05.017. Epub 2022 May 20. Acta Pharm Sin B. 2022. PMID: 36213537 Free PMC article.

4

iPSCs to the rescue in Alzheimer's research.

Choi SH, Tanzi RE. Choi SH, et al. Cell Stem Cell. 2012 Mar 2;10(3):235-6. doi: 10.1016/j.stem.2012.02.011. Cell Stem Cell. 2012. PMID: 22385650 Free article.

5

Alzheimer's in 3D culture: challenges and perspectives.

D'Avanzo C, Aronson J, Kim YH, Choi SH, Tanzi RE, Kim DY. D'Avanzo C, et al. Among authors: choi sh. Bioessays. 2015 Oct;37(10):1139-48. doi: 10.1002/bies.201500063. Epub 2015 Aug 7. Bioessays. 2015. PMID: 26252541 Free PMC article. Review.

6

3D culture models of Alzheimer's disease: a road map to a "cure-in-a-dish".

Choi SH, Kim YH, Quinti L, Tanzi RE, Kim DY. Choi SH, et al. Mol Neurodegener. 2016 Dec 9;11(1):75. doi: 10.1186/s13024-016-0139-7. Mol Neurodegener. 2016. PMID: 27938410 Free PMC article. Review.

7

Is Alzheimer's Disease a Neurogenesis Disorder?

Choi SH, Tanzi RE. Choi SH, et al. Cell Stem Cell. 2019 Jul 3;25(1):7-8. doi: 10.1016/j.stem.2019.06.001. Cell Stem Cell. 2019. PMID: 31271749 Free article.

8

Upregulation of Alzheimer's Disease Amyloid-β Protein Precursor in Astrocytes Both in vitro and in vivo.

Liang Y, Raven F, Ward JF, Zhen S, Zhang S, Sun H, Miller SJ, Choi SH, Tanzi RE, Zhang C. Liang Y, et al. Among authors: choi sh. J Alzheimers Dis. 2020;76(3):1071-1082. doi: 10.3233/JAD-200128. J Alzheimers Dis. 2020. PMID: 32597805 Free PMC article.

9

Molecular imaging of Alzheimer's disease-related gamma-secretase in mice and nonhuman primates.

Xu Y, Wang C, Wey HY, Liang Y, Chen Z, Choi SH, Ran C, Rynearson KD, Bernales DR, Koegel RE, Fiedler SA, Striar R, Wagner SL, Tanzi RE, Zhang C. Xu Y, et al. Among authors: choi sh. J Exp Med. 2020 Dec 7;217(12):e20182266. doi: 10.1084/jem.20182266. J Exp Med. 2020. PMID: 32936886 Free PMC article.

10

Degradation and inhibition of epigenetic regulatory protein BRD4 exacerbate Alzheimer's disease-related neuropathology in cell models.

Zhang S, Bai P, Lei D, Liang Y, Zhen S, Bakiasi G, Pang H, Choi SH, Wang C, Tanzi RE, Zhang C. Zhang S, et al. Among authors: choi sh. J Biol Chem. 2022 Apr;298(4):101794. doi: 10.1016/j.jbc.2022.101794. Epub 2022 Mar 3. J Biol Chem. 2022. PMID: 35248531 Free PMC article.

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