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Anti-LGALS3BP antibody-drug conjugate treatment induces durable and potent antitumor response in a preclinical model of adenoid cystic carcinoma.
Capone E, Perrotti V, Cela I, Lattanzio R, Togni L, Rubini C, Caponio VCA, Lo Muzio L, Colasante M, Giansanti F, Ippoliti R, Iacobelli S, Wick MJ, Spardy Burr N, Sala G. Capone E, et al. Among authors: lattanzio r. Oral Oncol. 2024 Jan;148:106635. doi: 10.1016/j.oraloncology.2023.106635. Epub 2023 Nov 21. Oral Oncol. 2024. PMID: 37988837 Free article.
High expression of 90K (Mac-2 BP) is associated with poor survival in node-negative breast cancer patients not receiving adjuvant systemic therapies.
Tinari N, Lattanzio R, Querzoli P, Natoli C, Grassadonia A, Alberti S, Hubalek M, Reimer D, Nenci I, Bruzzi P, Piantelli M, Iacobelli S; Consorzio Interuniversitario Nazionale per la Bio-Oncologia (CINBO). Tinari N, et al. Among authors: lattanzio r. Int J Cancer. 2009 Jan 15;124(2):333-8. doi: 10.1002/ijc.23970. Int J Cancer. 2009. PMID: 18942707 Free article.
Phospholipase Cgamma1 is required for metastasis development and progression.
Sala G, Dituri F, Raimondi C, Previdi S, Maffucci T, Mazzoletti M, Rossi C, Iezzi M, Lattanzio R, Piantelli M, Iacobelli S, Broggini M, Falasca M. Sala G, et al. Among authors: lattanzio r. Cancer Res. 2008 Dec 15;68(24):10187-96. doi: 10.1158/0008-5472.CAN-08-1181. Cancer Res. 2008. PMID: 19074886
An ErbB-3 antibody, MP-RM-1, inhibits tumor growth by blocking ligand-dependent and independent activation of ErbB-3/Akt signaling.
Sala G, Traini S, D'Egidio M, Vianale G, Rossi C, Piccolo E, Lattanzio R, Piantelli M, Tinari N, Natali PG, Muraro R, Iacobelli S; Consorzio Interuniversitario Nazionale per la Bio-Oncologia. Sala G, et al. Among authors: lattanzio r. Oncogene. 2012 Mar 8;31(10):1275-86. doi: 10.1038/onc.2011.322. Epub 2011 Aug 8. Oncogene. 2012. PMID: 21822299
Overexpression of activated phospholipase Cγ1 is a risk factor for distant metastases in T1-T2, N0 breast cancer patients undergoing adjuvant chemotherapy.
Lattanzio R, Marchisio M, La Sorda R, Tinari N, Falasca M, Alberti S, Miscia S, Ercolani C, Di Benedetto A, Perracchio L, Melucci E, Iacobelli S, Mottolese M, Natali PG, Piantelli M; CINBO (Consorzio Interuniversitario Nazionale per Bio-Oncologia). Lattanzio R, et al. Int J Cancer. 2013 Mar 1;132(5):1022-31. doi: 10.1002/ijc.27751. Epub 2012 Sep 1. Int J Cancer. 2013. PMID: 22847294 Free article.
LGALS3BP, lectin galactoside-binding soluble 3 binding protein, induces vascular endothelial growth factor in human breast cancer cells and promotes angiogenesis.
Piccolo E, Tinari N, Semeraro D, Traini S, Fichera I, Cumashi A, La Sorda R, Spinella F, Bagnato A, Lattanzio R, D'Egidio M, Di Risio A, Stampolidis P, Piantelli M, Natoli C, Ullrich A, Iacobelli S. Piccolo E, et al. Among authors: lattanzio r. J Mol Med (Berl). 2013 Jan;91(1):83-94. doi: 10.1007/s00109-012-0936-6. Epub 2012 Aug 5. J Mol Med (Berl). 2013. PMID: 22864925
Inhibition of tumor growth and angiogenesis by SP-2, an anti-lectin, galactoside-binding soluble 3 binding protein (LGALS3BP) antibody.
Traini S, Piccolo E, Tinari N, Rossi C, La Sorda R, Spinella F, Bagnato A, Lattanzio R, D'Egidio M, Di Risio A, Tomao F, Grassadonia A, Piantelli M, Natoli C, Iacobelli S. Traini S, et al. Among authors: lattanzio r. Mol Cancer Ther. 2014 Apr;13(4):916-25. doi: 10.1158/1535-7163.MCT-12-1117. Epub 2014 Feb 19. Mol Cancer Ther. 2014. PMID: 24552775
221 results