Cruite JT - Search Results

1

Covalent Stapling of the Cereblon Sensor Loop Histidine Using Sulfur-Heterocycle Exchange.

Cruite JT, Nowak RP, Donovan KA, Ficarro SB, Huang H, Liu H, Liu Y, Marto JA, Metivier RJ, Fischer ES, Jones LH. Cruite JT, et al. ACS Med Chem Lett. 2023 Oct 24;14(11):1576-1581. doi: 10.1021/acsmedchemlett.3c00371. eCollection 2023 Nov 9. ACS Med Chem Lett. 2023. PMID: 37974938

2

Cereblon covalent modulation through structure-based design of histidine targeting chemical probes.

Cruite JT, Dann GP, Che J, Donovan KA, Ferrao S, Ficarro SB, Fischer ES, Gray NS, Huerta F, Kong NR, Liu H, Marto JA, Metivier RJ, Nowak RP, Zerfas BL, Jones LH. Cruite JT, et al. RSC Chem Biol. 2022 Jul 8;3(9):1105-1110. doi: 10.1039/d2cb00078d. eCollection 2022 Aug 31. RSC Chem Biol. 2022. PMID: 36128501 Free PMC article.

3

Development of a covalent cereblon-based PROTAC employing a fluorosulfate warhead.

Nowak RP, Ragosta L, Huerta F, Liu H, Ficarro SB, Cruite JT, Metivier RJ, Donovan KA, Marto JA, Fischer ES, Zerfas BL, Jones LH. Nowak RP, et al. Among authors: cruite jt. RSC Chem Biol. 2023 Aug 31;4(11):906-912. doi: 10.1039/d3cb00103b. eCollection 2023 Nov 1. RSC Chem Biol. 2023. PMID: 37920397 Free PMC article.

4

Structural basis for virulence regulation in Vibrio cholerae by unsaturated fatty acid components of bile.

Cruite JT, Kovacikova G, Clark KA, Woodbrey AK, Skorupski K, Kull FJ. Cruite JT, et al. Commun Biol. 2019 Nov 28;2:440. doi: 10.1038/s42003-019-0686-x. eCollection 2019. Commun Biol. 2019. PMID: 31815195 Free PMC article.

5

Lack of prion infectivity in fixed heart tissue from patients with Creutzfeldt-Jakob disease or amyloid heart disease.

Priola SA, Ward AE, McCall SA, Trifilo M, Choi YP, Solforosi L, Williamson RA, Cruite JT, Oldstone MB. Priola SA, et al. Among authors: cruite jt. J Virol. 2013 Sep;87(17):9501-10. doi: 10.1128/JVI.00692-13. Epub 2013 Jun 19. J Virol. 2013. PMID: 23785217 Free PMC article.

6

Molecular anatomy and number of antigen specific CD8 T cells required to cause type 1 diabetes.

Oldstone MB, Edelmann KH, McGavern DB, Cruite JT, Welch MJ. Oldstone MB, et al. Among authors: cruite jt. PLoS Pathog. 2012;8(11):e1003044. doi: 10.1371/journal.ppat.1003044. Epub 2012 Nov 29. PLoS Pathog. 2012. PMID: 23209415 Free PMC article.

7

Disruption of copper homeostasis due to a mutation of Atp7a delays the onset of prion disease.

Siggs OM, Cruite JT, Du X, Rutschmann S, Masliah E, Beutler B, Oldstone MB. Siggs OM, et al. Among authors: cruite jt. Proc Natl Acad Sci U S A. 2012 Aug 21;109(34):13733-8. doi: 10.1073/pnas.1211499109. Epub 2012 Aug 6. Proc Natl Acad Sci U S A. 2012. PMID: 22869751 Free PMC article.

8

Histidines in the octapeptide repeat of PrPC react with PrPSc at an acidic pH.

Cruite JT, Abalos GC, Bellon A, Solforosi L. Cruite JT, et al. Biochemistry. 2011 Mar 15;50(10):1618-23. doi: 10.1021/bi1017683. Epub 2011 Feb 16. Biochemistry. 2011. PMID: 21268659

9

Identifying key components of the PrPC-PrPSc replicative interface.

Abalos GC, Cruite JT, Bellon A, Hemmers S, Akagi J, Mastrianni JA, Williamson RA, Solforosi L. Abalos GC, et al. Among authors: cruite jt. J Biol Chem. 2008 Dec 5;283(49):34021-8. doi: 10.1074/jbc.M804475200. Epub 2008 Sep 30. J Biol Chem. 2008. PMID: 18826953 Free PMC article.

10

Toward molecular dissection of PrPC-PrPSc interactions.

Solforosi L, Bellon A, Schaller M, Cruite JT, Abalos GC, Williamson RA. Solforosi L, et al. Among authors: cruite jt. J Biol Chem. 2007 Mar 9;282(10):7465-71. doi: 10.1074/jbc.M610051200. Epub 2007 Jan 10. J Biol Chem. 2007. PMID: 17218310 Free article.

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