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The cholesteryl ester transfer protein (CETP) raises cholesterol levels in the brain.
Oestereich F, Yousefpour N, Yang E, Phénix J, Nezhad ZS, Nitu A, Vázquez Cobá A, Ribeiro-da-Silva A, Chaurand P, Munter LM. Oestereich F, et al. Among authors: ribeiro da silva a. J Lipid Res. 2022 Sep;63(9):100260. doi: 10.1016/j.jlr.2022.100260. Epub 2022 Jul 31. J Lipid Res. 2022. PMID: 35921880 Free PMC article.
Intranasal insulin rescues repeated anesthesia-induced deficits in synaptic plasticity and memory and prevents apoptosis in neonatal mice via mTORC1.
Roque PS, Hooshmandi M, Neagu-Lund L, Yin S, Yousefpour N, Sato H, Sato T, Nakadate Y, Kawakami A, Tahmasebi S, Ribeiro-da-Silva A, Gkogkas CG, Prager-Khoutorsky M, Schricker T, Wykes L, Khoutorsky A. Roque PS, et al. Sci Rep. 2021 Jul 29;11(1):15490. doi: 10.1038/s41598-021-94849-3. Sci Rep. 2021. PMID: 34326413 Free PMC article.
Microglia-mediated degradation of perineuronal nets promotes pain.
Tansley S, Gu N, Guzmán AU, Cai W, Wong C, Lister KC, Muñoz-Pino E, Yousefpour N, Roome RB, Heal J, Wu N, Castonguay A, Lean G, Muir EM, Kania A, Prager-Khoutorsky M, Zhang J, Gkogkas CG, Fawcett JW, Diatchenko L, Ribeiro-da-Silva A, De Koninck Y, Mogil JS, Khoutorsky A. Tansley S, et al. Among authors: ribeiro da silva a. Science. 2022 Jul;377(6601):80-86. doi: 10.1126/science.abl6773. Epub 2022 May 26. Science. 2022. PMID: 35617374
mTORC2 mediates structural plasticity in distal nociceptive endings that contributes to pain hypersensitivity following inflammation.
Wong C, Barkai O, Wang F, Perez CT, Lev S, Cai W, Tansley S, Yousefpour N, Hooshmandi M, Lister KC, Latif M, Cuello AC, Prager-Khoutorsky M, Mogil JS, Séguéla P, De Koninck Y, Ribeiro-da-Silva A, Binshtok AM, Khoutorsky A. Wong C, et al. Among authors: ribeiro da silva a. J Clin Invest. 2022 Aug 1;132(15):e152635. doi: 10.1172/JCI152635. J Clin Invest. 2022. PMID: 35579957 Free PMC article.
161 results