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Inhibition of transforming growth factor-β signals suppresses tumor formation by regulation of tumor microenvironment networks.
Tokizaki S, Podyma-Inoue KA, Matsumoto T, Takahashi K, Kobayashi M, Ibi H, Uchida S, Iwabuchi S, Harada H, Hashimoto S, Miyazono K, Shirouzu M, Watabe T. Tokizaki S, et al. Among authors: miyazono k. Cancer Sci. 2024 Jan;115(1):211-226. doi: 10.1111/cas.16006. Epub 2023 Nov 16. Cancer Sci. 2024. PMID: 37972575 Free PMC article.
Targeting all transforming growth factor-β isoforms with an Fc chimeric receptor impairs tumor growth and angiogenesis of oral squamous cell cancer.
Takahashi K, Akatsu Y, Podyma-Inoue KA, Matsumoto T, Takahashi H, Yoshimatsu Y, Koinuma D, Shirouzu M, Miyazono K, Watabe T. Takahashi K, et al. Among authors: miyazono k. J Biol Chem. 2020 Sep 4;295(36):12559-12572. doi: 10.1074/jbc.RA120.012492. Epub 2020 Jul 6. J Biol Chem. 2020. PMID: 32631954 Free PMC article.
TGF-β generates a population of cancer cells residing in G1 phase with high motility and metastatic potential via KRTAP2-3.
Takahashi K, Podyma-Inoue KA, Saito M, Sakakitani S, Sugauchi A, Iida K, Iwabuchi S, Koinuma D, Kurioka K, Konishi T, Tanaka S, Kaida A, Miura M, Hashimoto S, Okada M, Uchihashi T, Miyazono K, Watabe T. Takahashi K, et al. Among authors: miyazono k. Cell Rep. 2022 Sep 27;40(13):111411. doi: 10.1016/j.celrep.2022.111411. Cell Rep. 2022. PMID: 36170816 Free article.
593 results