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Stress granules offer first aid for leaky organelles.
Plassmeyer SP, Holehouse AS. Plassmeyer SP, et al. Among authors: holehouse as. Nature. 2023 Nov;623(7989):919-920. doi: 10.1038/d41586-023-03417-4. Nature. 2023. PMID: 37968460 No abstract available.
Transcription factor dimerization activates the p300 acetyltransferase.
Ortega E, Rengachari S, Ibrahim Z, Hoghoughi N, Gaucher J, Holehouse AS, Khochbin S, Panne D. Ortega E, et al. Among authors: holehouse as. Nature. 2018 Oct;562(7728):538-544. doi: 10.1038/s41586-018-0621-1. Epub 2018 Oct 15. Nature. 2018. PMID: 30323286 Free PMC article.
The SARS-CoV-2 nucleocapsid protein is dynamic, disordered, and phase separates with RNA.
Cubuk J, Alston JJ, Incicco JJ, Singh S, Stuchell-Brereton MD, Ward MD, Zimmerman MI, Vithani N, Griffith D, Wagoner JA, Bowman GR, Hall KB, Soranno A, Holehouse AS. Cubuk J, et al. Among authors: holehouse as. Nat Commun. 2021 Mar 29;12(1):1936. doi: 10.1038/s41467-021-21953-3. Nat Commun. 2021. PMID: 33782395 Free PMC article.
Protein polymers: Encoding phase transitions.
Holehouse AS, Pappu RV. Holehouse AS, et al. Nat Mater. 2015 Nov;14(11):1083-4. doi: 10.1038/nmat4459. Nat Mater. 2015. PMID: 26490213 No abstract available.
Intrinsically disordered CO2 sensors.
Emenecker RJ, Holehouse AS. Emenecker RJ, et al. Among authors: holehouse as. Nat Cell Biol. 2022 Jul;24(7):1013-1014. doi: 10.1038/s41556-022-00957-1. Nat Cell Biol. 2022. PMID: 35790800 No abstract available.
Conformational buffering underlies functional selection in intrinsically disordered protein regions.
González-Foutel NS, Glavina J, Borcherds WM, Safranchik M, Barrera-Vilarmau S, Sagar A, Estaña A, Barozet A, Garrone NA, Fernandez-Ballester G, Blanes-Mira C, Sánchez IE, de Prat-Gay G, Cortés J, Bernadó P, Pappu RV, Holehouse AS, Daughdrill GW, Chemes LB. González-Foutel NS, et al. Among authors: holehouse as. Nat Struct Mol Biol. 2022 Aug;29(8):781-790. doi: 10.1038/s41594-022-00811-w. Epub 2022 Aug 10. Nat Struct Mol Biol. 2022. PMID: 35948766 Free PMC article.
Mapping from sequence to droplets.
Holehouse AS. Holehouse AS. Nat Rev Mol Cell Biol. 2021 Mar;22(3):163. doi: 10.1038/s41580-021-00333-1. Nat Rev Mol Cell Biol. 2021. PMID: 33473198 No abstract available.
95 results