Kunkel TA - Search Results

1

Stepwise requirements for polymerases δ and θ in theta-mediated end joining.

Stroik S, Carvajal-Garcia J, Gupta D, Edwards A, Luthman A, Wyatt DW, Dannenberg RL, Feng W, Kunkel TA, Gupta GP, Hedglin M, Wood R, Doublié S, Rothenberg E, Ramsden DA. Stroik S, et al. Among authors: kunkel ta. Nature. 2023 Nov;623(7988):836-841. doi: 10.1038/s41586-023-06729-7. Epub 2023 Nov 15. Nature. 2023. PMID: 37968395

2

Analysis of diverse double-strand break synapsis with Polλ reveals basis for unique substrate specificity in nonhomologous end-joining.

Kaminski AM, Chiruvella KK, Ramsden DA, Bebenek K, Kunkel TA, Pedersen LC. Kaminski AM, et al. Among authors: kunkel ta. Nat Commun. 2022 Jul 1;13(1):3806. doi: 10.1038/s41467-022-31278-4. Nat Commun. 2022. PMID: 35778389 Free PMC article.

3

Sustained active site rigidity during synthesis by human DNA polymerase μ.

Moon AF, Pryor JM, Ramsden DA, Kunkel TA, Bebenek K, Pedersen LC. Moon AF, et al. Among authors: kunkel ta. Nat Struct Mol Biol. 2014 Mar;21(3):253-60. doi: 10.1038/nsmb.2766. Epub 2014 Feb 2. Nat Struct Mol Biol. 2014. PMID: 24487959 Free PMC article.

4

Structural snapshots of human DNA polymerase μ engaged on a DNA double-strand break.

Kaminski AM, Pryor JM, Ramsden DA, Kunkel TA, Pedersen LC, Bebenek K. Kaminski AM, et al. Among authors: kunkel ta. Nat Commun. 2020 Sep 22;11(1):4784. doi: 10.1038/s41467-020-18506-5. Nat Commun. 2020. PMID: 32963245 Free PMC article.

5

A gradient of template dependence defines distinct biological roles for family X polymerases in nonhomologous end joining.

Nick McElhinny SA, Havener JM, Garcia-Diaz M, Juárez R, Bebenek K, Kee BL, Blanco L, Kunkel TA, Ramsden DA. Nick McElhinny SA, et al. Among authors: kunkel ta. Mol Cell. 2005 Aug 5;19(3):357-66. doi: 10.1016/j.molcel.2005.06.012. Mol Cell. 2005. PMID: 16061182 Free article.

6

Structural insight into the substrate specificity of DNA Polymerase mu.

Moon AF, Garcia-Diaz M, Bebenek K, Davis BJ, Zhong X, Ramsden DA, Kunkel TA, Pedersen LC. Moon AF, et al. Among authors: kunkel ta. Nat Struct Mol Biol. 2007 Jan;14(1):45-53. doi: 10.1038/nsmb1180. Epub 2006 Dec 10. Nat Struct Mol Biol. 2007. PMID: 17159995

7

Template strand scrunching during DNA gap repair synthesis by human polymerase lambda.

Garcia-Diaz M, Bebenek K, Larrea AA, Havener JM, Perera L, Krahn JM, Pedersen LC, Ramsden DA, Kunkel TA. Garcia-Diaz M, et al. Among authors: kunkel ta. Nat Struct Mol Biol. 2009 Sep;16(9):967-72. doi: 10.1038/nsmb.1654. Epub 2009 Aug 23. Nat Struct Mol Biol. 2009. PMID: 19701199 Free PMC article.

8

Structural accommodation of ribonucleotide incorporation by the DNA repair enzyme polymerase Mu.

Moon AF, Pryor JM, Ramsden DA, Kunkel TA, Bebenek K, Pedersen LC. Moon AF, et al. Among authors: kunkel ta. Nucleic Acids Res. 2017 Sep 6;45(15):9138-9148. doi: 10.1093/nar/gkx527. Nucleic Acids Res. 2017. PMID: 28911097 Free PMC article.

9

Unexpected behavior of DNA polymerase Mu opposite template 8-oxo-7,8-dihydro-2'-guanosine.

Kaminski AM, Chiruvella KK, Ramsden DA, Kunkel TA, Bebenek K, Pedersen LC. Kaminski AM, et al. Among authors: kunkel ta. Nucleic Acids Res. 2019 Sep 26;47(17):9410-9422. doi: 10.1093/nar/gkz680. Nucleic Acids Res. 2019. PMID: 31435651 Free PMC article.

10

Low-fidelity DNA synthesis by human DNA polymerase theta.

Arana ME, Seki M, Wood RD, Rogozin IB, Kunkel TA. Arana ME, et al. Among authors: kunkel ta. Nucleic Acids Res. 2008 Jun;36(11):3847-56. doi: 10.1093/nar/gkn310. Epub 2008 May 24. Nucleic Acids Res. 2008. PMID: 18503084 Free PMC article.

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