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A model-based approach leveraging in vitro data to support dose selection from the outset: A framework for bispecific antibodies in immuno-oncology.
Sánchez J, Claus C, Albrecht R, Gaillard BC, Marinho J, McIntyre C, Tanos T, Boehnke A, Friberg LE, Jönsson S, Frances N. Sánchez J, et al. Among authors: friberg le. CPT Pharmacometrics Syst Pharmacol. 2023 Nov;12(11):1804-1818. doi: 10.1002/psp4.13065. Epub 2023 Nov 15. CPT Pharmacometrics Syst Pharmacol. 2023. PMID: 37964753 Free PMC article.
Model-Based Characterization of the Bidirectional Interaction Between Pharmacokinetics and Tumor Growth Dynamics in Patients with Metastatic Merkel Cell Carcinoma Treated with Avelumab.
Grisic AM, Xiong W, Tanneau L, Jönsson S, Friberg LE, Karlsson MO, Dai H, Zheng J, Girard P, Khandelwal A. Grisic AM, et al. Among authors: friberg le. Clin Cancer Res. 2022 Apr 1;28(7):1363-1371. doi: 10.1158/1078-0432.CCR-21-2662. Clin Cancer Res. 2022. PMID: 34921021 Free PMC article.
Bayesian forecasting of tumor size metrics and overall survival.
Krishnan SM, Friberg LE. Krishnan SM, et al. Among authors: friberg le. CPT Pharmacometrics Syst Pharmacol. 2022 Dec;11(12):1604-1613. doi: 10.1002/psp4.12869. Epub 2022 Oct 4. CPT Pharmacometrics Syst Pharmacol. 2022. PMID: 36194478 Free PMC article.
A multistate modeling and simulation framework to learn dose-response of oncology drugs: Application to bintrafusp alfa in non-small cell lung cancer.
Liu H, Milenković-Grišić AM, Krishnan SM, Jönsson S, Friberg LE, Girard P, Venkatakrishnan K, Vugmeyster Y, Khandelwal A, Karlsson MO. Liu H, et al. Among authors: friberg le. CPT Pharmacometrics Syst Pharmacol. 2023 Nov;12(11):1738-1750. doi: 10.1002/psp4.12976. Epub 2023 May 11. CPT Pharmacometrics Syst Pharmacol. 2023. PMID: 37165943 Free PMC article.
186 results