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Hydroxytyrosol prevents reduction in liver activity of Δ-5 and Δ-6 desaturases, oxidative stress, and depletion in long chain polyunsaturated fatty acid content in different tissues of high-fat diet fed mice.
Valenzuela R, Echeverria F, Ortiz M, Rincón-Cervera MÁ, Espinosa A, Hernandez-Rodas MC, Illesca P, Valenzuela A, Videla LA. Valenzuela R, et al. Among authors: ortiz m. Lipids Health Dis. 2017 Apr 11;16(1):64. doi: 10.1186/s12944-017-0450-5. Lipids Health Dis. 2017. PMID: 28395666 Free PMC article.
Reduction of high-fat diet-induced liver proinflammatory state by eicosapentaenoic acid plus hydroxytyrosol supplementation: involvement of resolvins RvE1/2 and RvD1/2.
Echeverría F, Valenzuela R, Espinosa A, Bustamante A, Álvarez D, Gonzalez-Mañan D, Ortiz M, Soto-Alarcon SA, Videla LA. Echeverría F, et al. Among authors: ortiz m. J Nutr Biochem. 2019 Jan;63:35-43. doi: 10.1016/j.jnutbio.2018.09.012. Epub 2018 Sep 21. J Nutr Biochem. 2019. PMID: 30321750
Hydroxytyrosol supplementation ameliorates the metabolic disturbances in white adipose tissue from mice fed a high-fat diet through recovery of transcription factors Nrf2, SREBP-1c, PPAR-γ and NF-κB.
Illesca P, Valenzuela R, Espinosa A, Echeverría F, Soto-Alarcon S, Ortiz M, Videla LA. Illesca P, et al. Among authors: ortiz m. Biomed Pharmacother. 2019 Jan;109:2472-2481. doi: 10.1016/j.biopha.2018.11.120. Epub 2018 Dec 1. Biomed Pharmacother. 2019. PMID: 30551508 Free article.
Docosahexaenoic acid and hydroxytyrosol co-administration fully prevents liver steatosis and related parameters in mice subjected to high-fat diet: A molecular approach.
Soto-Alarcón SA, Ortiz M, Orellana P, Echeverría F, Bustamante A, Espinosa A, Illesca P, Gonzalez-Mañán D, Valenzuela R, Videla LA. Soto-Alarcón SA, et al. Among authors: ortiz m. Biofactors. 2019 Nov;45(6):930-943. doi: 10.1002/biof.1556. Epub 2019 Aug 27. Biofactors. 2019. PMID: 31454114
High-fat diet induces mouse liver steatosis with a concomitant decline in energy metabolism: attenuation by eicosapentaenoic acid (EPA) or hydroxytyrosol (HT) supplementation and the additive effects upon EPA and HT co-administration.
Echeverría F, Valenzuela R, Bustamante A, Álvarez D, Ortiz M, Espinosa A, Illesca P, Gonzalez-Mañan D, Videla LA. Echeverría F, et al. Among authors: ortiz m. Food Funct. 2019 Sep 1;10(9):6170-6183. doi: 10.1039/c9fo01373c. Epub 2019 Sep 10. Food Funct. 2019. PMID: 31501836
1,785 results