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Exploring the anticancer properties of a new nicotinamide analogue: Investigations into in silico analysis, antiproliferative effects, selectivity, VEGFR-2 inhibition, apoptosis induction, and migration suppression.
Eissa IH, Yousef RG, Sami M, Elkaeed EB, Alsfouk BA, Ibrahim IM, Husein DZ, Elkady H, Metwaly AM. Eissa IH, et al. Among authors: yousef rg. Pathol Res Pract. 2023 Dec;252:154924. doi: 10.1016/j.prp.2023.154924. Epub 2023 Nov 7. Pathol Res Pract. 2023. PMID: 37956639
Inhibition of Vascular Smooth Muscle and Cancer Cell Proliferation by New VEGFR Inhibitors and Their Immunomodulator Effect: Design, Synthesis, and Biological Evaluation.
Ran F, Li W, Qin Y, Yu T, Liu Z, Zhou M, Liu C, Qiao T, Li X, Yousef RG, Eissa IH, Khalifa MM. Ran F, et al. Among authors: yousef rg. Oxid Med Cell Longev. 2021 Oct 28;2021:8321400. doi: 10.1155/2021/8321400. eCollection 2021. Oxid Med Cell Longev. 2021. PMID: 34745424 Free PMC article.
Discovery of new nicotinamides as apoptotic VEGFR-2 inhibitors: virtual screening, synthesis, anti-proliferative, immunomodulatory, ADMET, toxicity, and molecular dynamic simulation studies.
Yousef RG, Ibrahim A, Khalifa MM, Eldehna WM, Gobaara IMM, Mehany ABM, Elkaeed EB, Alsfouk AA, Metwaly AM, Eissa IH. Yousef RG, et al. J Enzyme Inhib Med Chem. 2022 Dec;37(1):1389-1403. doi: 10.1080/14756366.2022.2070744. J Enzyme Inhib Med Chem. 2022. PMID: 35577416 Free PMC article.
26 results