Elkaeed EB - Search Results

1

Exploring the anticancer properties of a new nicotinamide analogue: Investigations into in silico analysis, antiproliferative effects, selectivity, VEGFR-2 inhibition, apoptosis induction, and migration suppression.

Eissa IH, Yousef RG, Sami M, Elkaeed EB, Alsfouk BA, Ibrahim IM, Husein DZ, Elkady H, Metwaly AM. Eissa IH, et al. Among authors: elkaeed eb. Pathol Res Pract. 2023 Dec;252:154924. doi: 10.1016/j.prp.2023.154924. Epub 2023 Nov 7. Pathol Res Pract. 2023. PMID: 37956639

2

Design, synthesis and anticancer evaluation of thieno[2,3-d]pyrimidine derivatives as dual EGFR/HER2 inhibitors and apoptosis inducers.

Elmetwally SA, Saied KF, Eissa IH, Elkaeed EB. Elmetwally SA, et al. Among authors: elkaeed eb. Bioorg Chem. 2019 Jul;88:102944. doi: 10.1016/j.bioorg.2019.102944. Epub 2019 Apr 25. Bioorg Chem. 2019. PMID: 31051400

3

Design and discovery of new 1,2,4-triazolo[4,3-c]quinazolines as potential DNA intercalators and topoisomerase II inhibitors.

Alesawy MS, Al-Karmalawy AA, Elkaeed EB, Alswah M, Belal A, Taghour MS, Eissa IH. Alesawy MS, et al. Among authors: elkaeed eb. Arch Pharm (Weinheim). 2021 Mar;354(3):e2000237. doi: 10.1002/ardp.202000237. Epub 2020 Nov 23. Arch Pharm (Weinheim). 2021. PMID: 33226150

4

Discovery of new quinolines as potent colchicine binding site inhibitors: design, synthesis, docking studies, and anti-proliferative evaluation.

Hagras M, El Deeb MA, Elzahabi HSA, Elkaeed EB, Mehany ABM, Eissa IH. Hagras M, et al. Among authors: elkaeed eb. J Enzyme Inhib Med Chem. 2021 Dec;36(1):640-658. doi: 10.1080/14756366.2021.1883598. J Enzyme Inhib Med Chem. 2021. PMID: 33588683 Free PMC article.

5

Comprehensive Virtual Screening of the Antiviral Potentialities of Marine Polycyclic Guanidine Alkaloids against SARS-CoV-2 (COVID-19).

El-Demerdash A, Metwaly AM, Hassan A, Abd El-Aziz TM, Elkaeed EB, Eissa IH, Arafa RK, Stockand JD. El-Demerdash A, et al. Among authors: elkaeed eb. Biomolecules. 2021 Mar 19;11(3):460. doi: 10.3390/biom11030460. Biomolecules. 2021. PMID: 33808721 Free PMC article.

6

Discovery of thieno[2,3-d]pyrimidine-based derivatives as potent VEGFR-2 kinase inhibitors and anti-cancer agents.

El-Metwally SA, Abou-El-Regal MM, Eissa IH, Mehany ABM, Mahdy HA, Elkady H, Elwan A, Elkaeed EB. El-Metwally SA, et al. Among authors: elkaeed eb. Bioorg Chem. 2021 Jul;112:104947. doi: 10.1016/j.bioorg.2021.104947. Epub 2021 Apr 27. Bioorg Chem. 2021. PMID: 33964580

7

Molecular Docking and Dynamics Simulation Revealed the Potential Inhibitory Activity of ACEIs Against SARS-CoV-2 Targeting the hACE2 Receptor.

Al-Karmalawy AA, Dahab MA, Metwaly AM, Elhady SS, Elkaeed EB, Eissa IH, Darwish KM. Al-Karmalawy AA, et al. Among authors: elkaeed eb. Front Chem. 2021 May 4;9:661230. doi: 10.3389/fchem.2021.661230. eCollection 2021. Front Chem. 2021. PMID: 34017819 Free PMC article.

8

In Silico Studies of Some Isoflavonoids as Potential Candidates against COVID-19 Targeting Human ACE2 (hACE2) and Viral Main Protease (M^pro).

Alesawy MS, Abdallah AE, Taghour MS, Elkaeed EB, H Eissa I, Metwaly AM. Alesawy MS, et al. Among authors: elkaeed eb. Molecules. 2021 May 10;26(9):2806. doi: 10.3390/molecules26092806. Molecules. 2021. PMID: 34068579 Free PMC article.

9

In Silico Exploration of Potential Natural Inhibitors against SARS-Cov-2 nsp10.

Eissa IH, Khalifa MM, Elkaeed EB, Hafez EE, Alsfouk AA, Metwaly AM. Eissa IH, et al. Among authors: elkaeed eb. Molecules. 2021 Oct 12;26(20):6151. doi: 10.3390/molecules26206151. Molecules. 2021. PMID: 34684735 Free PMC article.

10

In Silico Screening of Semi-Synthesized Compounds as Potential Inhibitors for SARS-CoV-2 Papain-like Protease: Pharmacophoric Features, Molecular Docking, ADMET, Toxicity and DFT Studies.

Alesawy MS, Elkaeed EB, Alsfouk AA, Metwaly AM, Eissa IH. Alesawy MS, et al. Among authors: elkaeed eb. Molecules. 2021 Oct 30;26(21):6593. doi: 10.3390/molecules26216593. Molecules. 2021. PMID: 34771004 Free PMC article.

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