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Exploring switch II pocket conformation of KRAS(G12D) with mutant-selective monobody inhibitors.
Akkapeddi P, Hattori T, Khan I, Glasser E, Koide A, Ketavarapu G, Whaby M, Zuberi M, Teng KW, Lefler J, Maso L, Bang I, Ostrowski MC, O'Bryan JP, Koide S. Akkapeddi P, et al. Among authors: o bryan jp. Proc Natl Acad Sci U S A. 2023 Jul 11;120(28):e2302485120. doi: 10.1073/pnas.2302485120. Epub 2023 Jul 3. Proc Natl Acad Sci U S A. 2023. PMID: 37399416 Free PMC article.
HSP70-mediated mitochondrial dynamics and autophagy represent a novel vulnerability in pancreatic cancer.
Ferretti GDS, Quaas CE, Bertolini I, Zuccotti A, Saatci O, Kashatus JA, Sharmin S, Lu DY, Poli ANR, Quesnelle AF, Rodriguez-Blanco J, de Cubas AA, Hobbs GA, Liu Q, O'Bryan JP, Salvino JM, Kashatus DF, Sahin O, Barnoud T. Ferretti GDS, et al. Among authors: o bryan jp. Cell Death Differ. 2024 May 28. doi: 10.1038/s41418-024-01310-9. Online ahead of print. Cell Death Differ. 2024. PMID: 38802657
Intersectin - many facets of a scaffold protein.
Mintoo M, Rajagopalan V, O'Bryan JP. Mintoo M, et al. Among authors: o bryan jp. Biochem Soc Trans. 2024 Feb 28;52(1):1-13. doi: 10.1042/BST20211241. Biochem Soc Trans. 2024. PMID: 38174740 Review.
Ceramide synthase 6 impacts T-cell allogeneic response and graft-versus-host disease through regulating N-RAS/ERK pathway.
Sofi MH, Tian L, Schutt S, Khan I, Choi HJ, Wu Y, Bastian D, Ticer T, Kassir MF, Atilgan FC, Kim J, Sui X, Zivkovic A, Mehrotra S, O'Bryan JP, Stark H, Martin PJ, Ogretmen B, Yu XZ. Sofi MH, et al. Among authors: o bryan jp. Leukemia. 2022 Jul;36(7):1907-1915. doi: 10.1038/s41375-022-01581-6. Epub 2022 May 5. Leukemia. 2022. PMID: 35513703 Free PMC article.
Preface.
O'Bryan JP, Piazza GA. O'Bryan JP, et al. Adv Cancer Res. 2022;153:xiii-xiv. doi: 10.1016/S0065-230X(22)00012-4. Adv Cancer Res. 2022. PMID: 35101237 No abstract available.
75 results