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Resistance to Enediyne Antitumor Antibiotics by Sequestration.
Chang CY, Yan X, Crnovcic I, Annaval T, Chang C, Nocek B, Rudolf JD, Yang D, Hindra, Babnigg G, Joachimiak A, Phillips GN Jr, Shen B. Chang CY, et al. Among authors: chang c. Cell Chem Biol. 2018 Sep 20;25(9):1075-1085.e4. doi: 10.1016/j.chembiol.2018.05.012. Epub 2018 Jun 21. Cell Chem Biol. 2018. PMID: 29937405 Free PMC article.
Crystal structure of SgcJ, an NTF2-like superfamily protein involved in biosynthesis of the nine-membered enediyne antitumor antibiotic C-1027.
Huang T, Chang CY, Lohman JR, Rudolf JD, Kim Y, Chang C, Yang D, Ma M, Yan X, Crnovcic I, Bigelow L, Clancy S, Bingman CA, Yennamalli RM, Babnigg G, Joachimiak A, Phillips GN, Shen B. Huang T, et al. Among authors: chang c, chang cy. J Antibiot (Tokyo). 2016 Oct;69(10):731-740. doi: 10.1038/ja.2016.88. Epub 2016 Jul 13. J Antibiot (Tokyo). 2016. PMID: 27406907 Free PMC article.
Crystal Structure of the Zorbamycin-Binding Protein ZbmA, the Primary Self-Resistance Element in Streptomyces flavoviridis ATCC21892.
Rudolf JD, Bigelow L, Chang C, Cuff ME, Lohman JR, Chang CY, Ma M, Yang D, Clancy S, Babnigg G, Joachimiak A, Phillips GN Jr, Shen B. Rudolf JD, et al. Among authors: chang c, chang cy. Biochemistry. 2015 Nov 17;54(45):6842-51. doi: 10.1021/acs.biochem.5b01008. Epub 2015 Nov 5. Biochemistry. 2015. PMID: 26512730 Free PMC article.
Structural and evolutionary relationships of "AT-less" type I polyketide synthase ketosynthases.
Lohman JR, Ma M, Osipiuk J, Nocek B, Kim Y, Chang C, Cuff M, Mack J, Bigelow L, Li H, Endres M, Babnigg G, Joachimiak A, Phillips GN Jr, Shen B. Lohman JR, et al. Among authors: chang c. Proc Natl Acad Sci U S A. 2015 Oct 13;112(41):12693-8. doi: 10.1073/pnas.1515460112. Epub 2015 Sep 29. Proc Natl Acad Sci U S A. 2015. PMID: 26420866 Free PMC article.
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