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Manipulating the 3D organization of the largest synthetic yeast chromosome.
Mol Cell. 2023 Dec 7;83(23):4424-4437.e5. doi: 10.1016/j.molcel.2023.10.015. Epub 2023 Nov 8.
Mol Cell. 2023.
PMID: 37944526
Free article.
CREEPY: CRISPR-mediated editing of synthetic episomes in yeast.
Zhao Y, Coelho C, Lauer S, Majewski M, Laurent JM, Brosh R, Boeke JD.
Zhao Y, et al.
Nucleic Acids Res. 2023 Jul 21;51(13):e72. doi: 10.1093/nar/gkad491.
Nucleic Acids Res. 2023.
PMID: 37326023
Free PMC article.
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Debugging and consolidating multiple synthetic chromosomes reveals combinatorial genetic interactions.
Zhao Y, Coelho C, Hughes AL, Lazar-Stefanita L, Yang S, Brooks AN, Walker RSK, Zhang W, Lauer S, Hernandez C, Cai J, Mitchell LA, Agmon N, Shen Y, Sall J, Fanfani V, Jalan A, Rivera J, Liang FX, Bader JS, Stracquadanio G, Steinmetz LM, Cai Y, Boeke JD.
Zhao Y, et al.
Cell. 2023 Nov 22;186(24):5220-5236.e16. doi: 10.1016/j.cell.2023.09.025. Epub 2023 Nov 8.
Cell. 2023.
PMID: 37944511
Free article.
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Synthetic chromosome fusion: Effects on mitotic and meiotic genome structure and function.
Luo J, Vale-Silva LA, Raghavan AR, Mercy G, Heldrich J, Sun X, Li MK, Zhang W, Agmon N, Yang K, Cai J, Stracquadanio G, Thierry A, Zhao Y, Coelho C, McCulloch LH, Lauer S; Build-A-Genome Class; Kaback DB, Bader JS, Mitchell LA, Mozziconacci J, Koszul R, Hochwagen A, Boeke JD.
Luo J, et al.
Cell Genom. 2023 Nov 9;3(11):100439. doi: 10.1016/j.xgen.2023.100439. eCollection 2023 Nov 8.
Cell Genom. 2023.
PMID: 38020967
Free PMC article.
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Context-dependent neocentromere activity in synthetic yeast chromosome VIII.
Lauer S, Luo J, Lazar-Stefanita L, Zhang W, McCulloch LH, Fanfani V, Lobzaev E, Haase MAB, Easo N, Zhao Y, Yu F, Cai J; Build-A-Genome Class; Bader JS, Stracquadanio G, Boeke JD.
Lauer S, et al.
Cell Genom. 2023 Nov 9;3(11):100437. doi: 10.1016/j.xgen.2023.100437. eCollection 2023 Nov 8.
Cell Genom. 2023.
PMID: 38020969
Free PMC article.
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Synthetic yeast chromosome XI design provides a testbed for the study of extrachromosomal circular DNA dynamics.
Blount BA, Lu X, Driessen MRM, Jovicevic D, Sanchez MI, Ciurkot K, Zhao Y, Lauer S, McKiernan RM, Gowers GF, Sweeney F, Fanfani V, Lobzaev E, Palacios-Flores K, Walker RSK, Hesketh A, Cai J, Oliver SG, Cai Y, Stracquadanio G, Mitchell LA, Bader JS, Boeke JD, Ellis T.
Blount BA, et al.
Cell Genom. 2023 Nov 9;3(11):100418. doi: 10.1016/j.xgen.2023.100418. eCollection 2023 Nov 8.
Cell Genom. 2023.
PMID: 38020971
Free PMC article.
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Transport Home and Terminal Extubation by Emergency Medical Services: An Example of Innovation in End-of-Life Care.
Clemency BM, Grimm KT, Lauer SL, Lynch JC, Pastwik BL, Lindstrom HA, Dailey MW, Waldrop DP.
Clemency BM, et al. Among authors: lauer sl.
J Pain Symptom Manage. 2019 Aug;58(2):355-359. doi: 10.1016/j.jpainsymman.2019.03.007. Epub 2019 Mar 21.
J Pain Symptom Manage. 2019.
PMID: 30904415
Free article.
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Spared piriform cortical single-unit odor processing and odor discrimination in the Tg2576 mouse model of Alzheimer's disease.
Xu W, Lopez-Guzman M, Schoen C, Fitzgerald S, Lauer SL, Nixon RA, Levy E, Wilson DA.
Xu W, et al. Among authors: lauer sl.
PLoS One. 2014 Sep 2;9(9):e106431. doi: 10.1371/journal.pone.0106431. eCollection 2014.
PLoS One. 2014.
PMID: 25181487
Free PMC article.
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