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Targeting hyperactive platelet-derived growth factor receptor-β signaling in T-cell acute lymphoblastic leukemia and lymphoma.
De Coninck S, De Smedt R, Lintermans B, Reunes L, Kosasih HJ, Reekmans A, Brown LM, Van Roy N, Palhais B, Roels J, Van der Linden M, Van Dorpe J, Ntziachristos P, Van Delft FW, Mansour MR, Pieters T, Lammens T, De Moerloose B, De Bock CE, Goossens S, Van Vlierberghe P. De Coninck S, et al. Among authors: de bock ce. Haematologica. 2024 May 1;109(5):1373-1384. doi: 10.3324/haematol.2023.283981. Haematologica. 2024. PMID: 37941480 Free PMC article.
ABT-199 mediated inhibition of BCL-2 as a novel therapeutic strategy in T-cell acute lymphoblastic leukemia.
Peirs S, Matthijssens F, Goossens S, Van de Walle I, Ruggero K, de Bock CE, Degryse S, Canté-Barrett K, Briot D, Clappier E, Lammens T, De Moerloose B, Benoit Y, Poppe B, Meijerink JP, Cools J, Soulier J, Rabbitts TH, Taghon T, Speleman F, Van Vlierberghe P. Peirs S, et al. Among authors: de moerloose b, de bock ce. Blood. 2014 Dec 11;124(25):3738-47. doi: 10.1182/blood-2014-05-574566. Epub 2014 Oct 9. Blood. 2014. PMID: 25301704 Free article.
Mutant JAK3 phosphoproteomic profiling predicts synergism between JAK3 inhibitors and MEK/BCL2 inhibitors for the treatment of T-cell acute lymphoblastic leukemia.
Degryse S, de Bock CE, Demeyer S, Govaerts I, Bornschein S, Verbeke D, Jacobs K, Binos S, Skerrett-Byrne DA, Murray HC, Verrills NM, Van Vlierberghe P, Cools J, Dun MD. Degryse S, et al. Among authors: de bock ce. Leukemia. 2018 Mar;32(3):788-800. doi: 10.1038/leu.2017.276. Epub 2017 Aug 30. Leukemia. 2018. PMID: 28852199 Free PMC article.
A comprehensive inventory of TLX1 controlled long non-coding RNAs in T-cell acute lymphoblastic leukemia through polyA+ and total RNA sequencing.
Verboom K, Van Loocke W, Volders PJ, Decaesteker B, Cobos FA, Bornschein S, de Bock CE, Atak ZK, Clappier E, Aerts S, Cools J, Soulier J, Taghon T, Van Vlierberghe P, Vandesompele J, Speleman F, Durinck K. Verboom K, et al. Among authors: de bock ce. Haematologica. 2018 Dec;103(12):e585-e589. doi: 10.3324/haematol.2018.190587. Epub 2018 Jun 28. Haematologica. 2018. PMID: 29954933 Free PMC article. No abstract available.
T-cell acute lymphoblastic leukemias express a unique truncated FAT1 isoform that cooperates with NOTCH1 in leukemia development.
de Bock CE, Down M, Baidya K, Sweron B, Boyd AW, Fiers M, Burns GF, Molloy TJ, Lock RB, Soulier J, Taghon T, Van Vlierberghe P, Cools J, Holst J, Thorne RF. de Bock CE, et al. Haematologica. 2019 May;104(5):e204-e207. doi: 10.3324/haematol.2018.198424. Epub 2018 Dec 4. Haematologica. 2019. PMID: 30514801 Free PMC article. No abstract available.
Unusual PDGFRB fusion reveals novel mechanism of kinase activation in Ph-like B-ALL.
Sadras T, Jalud FB, Kosasih HJ, Horne CR, Brown LM, El-Kamand S, de Bock CE, McAloney L, Ng AP, Davidson NM, Ludlow LEA, Oshlack A, Cowley MJ, Khaw SL, Murphy JM, Ekert PG. Sadras T, et al. Among authors: de bock ce. Leukemia. 2023 Apr;37(4):905-909. doi: 10.1038/s41375-023-01843-x. Epub 2023 Feb 21. Leukemia. 2023. PMID: 36810896 Free PMC article. No abstract available.
Correction: Mutant JAK3 phosphoproteomic profiling predicts synergism between JAK3 inhibitors and MEK/BCL2 inhibitors for the treatment of T-cell acute lymphoblastic leukemia.
Degryse S, de Bock CE, Demeyer S, Govaerts I, Bornschein S, Verbeke D, Jacobs K, Binos S, Skerrett-Byrne DA, Murray HC, Verrills NM, Van Vlierberghe P, Cools J, Dun MD. Degryse S, et al. Among authors: de bock ce. Leukemia. 2018 Dec;32(12):2731. doi: 10.1038/s41375-018-0241-7. Leukemia. 2018. PMID: 30232463 Free PMC article.
68 results