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PDP1 is a key metabolic gatekeeper and modulator of drug resistance in FLT3-ITD-positive acute myeloid leukemia.
Alshamleh I, Kurrle N, Makowka P, Bhayadia R, Kumar R, Süsser S, Seibert M, Ludig D, Wolf S, Koschade SE, Stoschek K, Kreitz J, Fuhrmann DC, Toenges R, Notaro M, Comoglio F, Schuringa JJ, Berg T, Brüne B, Krause DS, Klusmann JH, Oellerich T, Schnütgen F, Schwalbe H, Serve H. Alshamleh I, et al. Among authors: ludig d. Leukemia. 2023 Dec;37(12):2367-2382. doi: 10.1038/s41375-023-02041-5. Epub 2023 Nov 7. Leukemia. 2023. PMID: 37935978 Free PMC article.
Optimization of the Lead Compound NVP-BHG712 as a Colorectal Cancer Inhibitor.
Tröster A, DiPrima M, Jores N, Kudlinzki D, Sreeramulu S, Gande SL, Linhard V, Ludig D, Schug A, Saxena K, Reinecke M, Heinzlmeir S, Leisegang MS, Wollenhaupt J, Lennartz F, Weiss MS, Kuster B, Tosato G, Schwalbe H. Tröster A, et al. Among authors: ludig d. Chemistry. 2023 Apr 21;29(23):e202203967. doi: 10.1002/chem.202203967. Epub 2023 Mar 22. Chemistry. 2023. PMID: 36799129 Free PMC article.
VitroJet: new features and case studies.
Henderikx RJM, Mann D, Domanska A, Dong J, Shahzad S, Lak B, Filopoulou A, Ludig D, Grininger M, Momoh J, Laanto E, Oksanen HM, Bisikalo K, Williams PA, Butcher SJ, Peters PJ, Beulen BWAMM. Henderikx RJM, et al. Among authors: ludig d. Acta Crystallogr D Struct Biol. 2024 Apr 1;80(Pt 4):232-246. doi: 10.1107/S2059798324001852. Epub 2024 Mar 15. Acta Crystallogr D Struct Biol. 2024. PMID: 38488730 Free PMC article.