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CRISPR-Cas9-based functional interrogation of unconventional translatome reveals human cancer dependency on cryptic non-canonical open reading frames.
Zheng C, Wei Y, Zhang P, Lin K, He D, Teng H, Manyam G, Zhang Z, Liu W, Lee HRL, Tang X, He W, Islam N, Jain A, Chiu Y, Cao S, Diao Y, Meyer-Gauen S, Höök M, Malovannaya A, Li W, Hu M, Wang W, Xu H, Kopetz S, Chen Y. Zheng C, et al. Among authors: chen y. Nat Struct Mol Biol. 2023 Dec;30(12):1878-1892. doi: 10.1038/s41594-023-01117-1. Epub 2023 Nov 6. Nat Struct Mol Biol. 2023. PMID: 37932451 Free PMC article.
The Emerging Function and Mechanism of ceRNAs in Cancer.
Wang Y, Hou J, He D, Sun M, Zhang P, Yu Y, Chen Y. Wang Y, et al. Among authors: chen y. Trends Genet. 2016 Apr;32(4):211-224. doi: 10.1016/j.tig.2016.02.001. Epub 2016 Feb 24. Trends Genet. 2016. PMID: 26922301 Free PMC article. Review.
Genome-wide identification and differential analysis of translational initiation.
Zhang P, He D, Xu Y, Hou J, Pan BF, Wang Y, Liu T, Davis CM, Ehli EA, Tan L, Zhou F, Hu J, Yu Y, Chen X, Nguyen TM, Rosen JM, Hawke DH, Ji Z, Chen Y. Zhang P, et al. Among authors: chen x, chen y. Nat Commun. 2017 Nov 23;8(1):1749. doi: 10.1038/s41467-017-01981-8. Nat Commun. 2017. PMID: 29170441 Free PMC article.
FGFR1-Activated Translation of WNT Pathway Components with Structured 5' UTRs Is Vulnerable to Inhibition of EIF4A-Dependent Translation Initiation.
Nguyen TM, Kabotyanski EB, Dou Y, Reineke LC, Zhang P, Zhang XH, Malovannaya A, Jung SY, Mo Q, Roarty KP, Chen Y, Zhang B, Neilson JR, Lloyd RE, Perou CM, Ellis MJ, Rosen JM. Nguyen TM, et al. Among authors: chen y. Cancer Res. 2018 Aug 1;78(15):4229-4240. doi: 10.1158/0008-5472.CAN-18-0631. Epub 2018 May 29. Cancer Res. 2018. PMID: 29844125 Free PMC article.
166,229 results
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