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Autophagy-mediated control of ribosome homeostasis in oncogene-induced senescence.
López AR, Jørgensen MH, Havelund JF, Arendrup FS, Kolapalli SP, Nielsen TM, Pais E, Beese CJ, Abdul-Al A, Vind AC, Bartek J, Bekker-Jensen S, Montes M, Galanos P, Faergeman N, Happonen L, Frankel LB. López AR, et al. Among authors: frankel lb. Cell Rep. 2023 Nov 28;42(11):113381. doi: 10.1016/j.celrep.2023.113381. Epub 2023 Nov 5. Cell Rep. 2023. PMID: 37930887 Free article.
Autophagy role(s) in response to oncogenes and DNA replication stress.
Vanzo R, Bartkova J, Merchut-Maya JM, Hall A, Bouchal J, Dyrskjøt L, Frankel LB, Gorgoulis V, Maya-Mendoza A, Jäättelä M, Bartek J. Vanzo R, et al. Among authors: frankel lb. Cell Death Differ. 2020 Mar;27(3):1134-1153. doi: 10.1038/s41418-019-0403-9. Epub 2019 Aug 14. Cell Death Differ. 2020. PMID: 31409894 Free PMC article.
Selective autophagy maintains centrosome integrity and accurate mitosis by turnover of centriolar satellites.
Holdgaard SG, Cianfanelli V, Pupo E, Lambrughi M, Lubas M, Nielsen JC, Eibes S, Maiani E, Harder LM, Wesch N, Foged MM, Maeda K, Nazio F, de la Ballina LR, Dötsch V, Brech A, Frankel LB, Jäättelä M, Locatelli F, Barisic M, Andersen JS, Bekker-Jensen S, Lund AH, Rogov VV, Papaleo E, Lanzetti L, De Zio D, Cecconi F. Holdgaard SG, et al. Among authors: frankel lb. Nat Commun. 2019 Sep 13;10(1):4176. doi: 10.1038/s41467-019-12094-9. Nat Commun. 2019. PMID: 31519908 Free PMC article.
Spatial-proteomics reveals phospho-signaling dynamics at subcellular resolution.
Martinez-Val A, Bekker-Jensen DB, Steigerwald S, Koenig C, Østergaard O, Mehta A, Tran T, Sikorski K, Torres-Vega E, Kwasniewicz E, Brynjólfsdóttir SH, Frankel LB, Kjøbsted R, Krogh N, Lundby A, Bekker-Jensen S, Lund-Johansen F, Olsen JV. Martinez-Val A, et al. Among authors: frankel lb. Nat Commun. 2021 Dec 7;12(1):7113. doi: 10.1038/s41467-021-27398-y. Nat Commun. 2021. PMID: 34876567 Free PMC article.
Measuring Autophagic Cargo Flux with Keima-Based Probes.
Engedal N, Sønstevold T, Beese CJ, Selladurai S, Melcher T, Simensen JE, Frankel LB, Urbanucci A, Torgersen ML. Engedal N, et al. Among authors: frankel lb. Methods Mol Biol. 2022;2445:99-115. doi: 10.1007/978-1-0716-2071-7_7. Methods Mol Biol. 2022. PMID: 34972988
Ribosome stalling is a signal for metabolic regulation by the ribotoxic stress response.
Snieckute G, Genzor AV, Vind AC, Ryder L, Stoneley M, Chamois S, Dreos R, Nordgaard C, Sass F, Blasius M, López AR, Brynjólfsdóttir SH, Andersen KL, Willis AE, Frankel LB, Poulsen SS, Gatfield D, Gerhart-Hines Z, Clemmensen C, Bekker-Jensen S. Snieckute G, et al. Among authors: frankel lb. Cell Metab. 2022 Dec 6;34(12):2036-2046.e8. doi: 10.1016/j.cmet.2022.10.011. Epub 2022 Nov 15. Cell Metab. 2022. PMID: 36384144 Free PMC article.
32 results