Kim HR - Search Results

1

Discovery of Chemical Scaffolds as Lysophosphatidic Acid Receptor 1 Antagonists: Virtual Screening, In Vitro Validation, and Molecular Dynamics Analysis.

Nguyen LP, Khan RA, Kang S, Lee H, Hwang JI, Kim HR. Nguyen LP, et al. Among authors: kim hr. ACS Omega. 2023 Oct 18;8(43):40375-40386. doi: 10.1021/acsomega.3c04798. eCollection 2023 Oct 31. ACS Omega. 2023. PMID: 37929144 Free PMC article.

2

SP-8356 inhibits acute lung injury by suppressing inflammatory cytokine production and immune cell infiltration.

Nguyen TU, Hurh S, In S, Nguyen LP, Cho M, Mykhailova K, Kim HR, Ham BJ, Choi Y, Kim WK, Hwang JI. Nguyen TU, et al. Among authors: kim wk, kim hr. Int Immunopharmacol. 2024 Apr 20;131:111847. doi: 10.1016/j.intimp.2024.111847. Epub 2024 Mar 21. Int Immunopharmacol. 2024. PMID: 38518593

3

Synthesis of 9-Cinnamyl-9H-purine Derivatives as Novel TLR4/MyD88/NF-κB Pathway Inhibitors for Anti-inflammatory Effects.

Pham L, Jiang R, Liu Z, Nguyen M, Nguyen Y, Gong Y, Bi Y, Kim HR, Kim YR, Kim G. Pham L, et al. Among authors: kim g, kim yr, kim hr. ACS Med Chem Lett. 2023 Nov 27;14(12):1839-1847. doi: 10.1021/acsmedchemlett.3c00437. eCollection 2023 Dec 14. ACS Med Chem Lett. 2023. PMID: 38116448

4

Dual-Specificity Tyrosine Phosphorylation-Regulated Kinase 1A (DYRK1A) Inhibitors as Potential Therapeutics.

Jarhad DB, Mashelkar KK, Kim HR, Noh M, Jeong LS. Jarhad DB, et al. Among authors: kim hr. J Med Chem. 2018 Nov 21;61(22):9791-9810. doi: 10.1021/acs.jmedchem.8b00185. Epub 2018 Jul 20. J Med Chem. 2018. PMID: 29985601 Review.

5

Synthesis of Enantiomerically Pure Pyrimidine Ribonucleosides Locked in the South Conformation.

Hyun YE, Jarhad DB, Kim M, Yang A, Kim G, Kim HR, Jeong LS. Hyun YE, et al. Among authors: kim g, kim m, kim hr. Org Lett. 2022 Dec 23;24(50):9281-9284. doi: 10.1021/acs.orglett.2c03853. Epub 2022 Dec 13. Org Lett. 2022. PMID: 36512445

6

Structure-Activity Relationships of Truncated 1'-Homologated Carbaadenosine Derivatives as New PPARγ/δ Ligands: A Study on Sugar Puckering Affecting Binding to PPARs.

Hyun YE, An S, Kim M, Park IG, Yoon S, Javaid HMA, Vu TNL, Kim G, Choi H, Lee HW, Noh M, Huh JY, Choi S, Kim HR, Jeong LS. Hyun YE, et al. Among authors: kim g, kim m, kim hr. J Med Chem. 2023 Apr 13;66(7):4961-4978. doi: 10.1021/acs.jmedchem.2c02071. Epub 2023 Mar 26. J Med Chem. 2023. PMID: 36967575

7

Stereoselective Synthesis of (S)- and (N)-Cyclopropyl-Fused Carbocyclic Nucleosides Using Stereoselective Cyclopropanation.

Hyun YE, Kim HR, Jeong LS. Hyun YE, et al. Among authors: kim hr. J Org Chem. 2021 Jul 16;86(14):9828-9837. doi: 10.1021/acs.joc.1c00705. Epub 2021 Jun 29. J Org Chem. 2021. PMID: 34184528

8

UBC12-mediated SREBP-1 neddylation worsens metastatic tumor prognosis.

Heo MJ, Kang SH, Kim YS, Lee JM, Yu J, Kim HR, Lim H, Kim KM, Jung J, Jeong LS, Moon A, Kim SG. Heo MJ, et al. Among authors: kim km, kim sg, kim ys, kim hr. Int J Cancer. 2020 Nov 1;147(9):2550-2563. doi: 10.1002/ijc.33113. Epub 2020 Jun 23. Int J Cancer. 2020. PMID: 32449166 Free article.

9

Design, Synthesis, and Anti-RNA Virus Activity of 6'-Fluorinated-Aristeromycin Analogues.

Yoon JS, Kim G, Jarhad DB, Kim HR, Shin YS, Qu S, Sahu PK, Kim HO, Lee HW, Wang SB, Kong YJ, Chang TS, Ogando NS, Kovacikova K, Snijder EJ, Posthuma CC, van Hemert MJ, Jeong LS. Yoon JS, et al. Among authors: kim g, kim ho, kim hr. J Med Chem. 2019 Jul 11;62(13):6346-6362. doi: 10.1021/acs.jmedchem.9b00781. Epub 2019 Jun 20. J Med Chem. 2019. PMID: 31244113 Free PMC article.

10

Discovery of a Tunable Heterocyclic Electrophile 4-Chloro-pyrazolopyridine That Defines a Unique Subset of Ligandable Cysteines.

Kim HR, Byun DP, Thakur K, Ritchie J, Xie Y, Holewinski R, Suazo KF, Stevens M, Liechty H, Tagirasa R, Jing Y, Andresson T, Johnson SM, Yoo E. Kim HR, et al. ACS Chem Biol. 2024 May 17;19(5):1082-1092. doi: 10.1021/acschembio.4c00025. Epub 2024 Apr 17. ACS Chem Biol. 2024. PMID: 38629450

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