Brooks DL - Search Results

1

A base editing strategy using mRNA-LNPs for in vivo correction of the most frequent phenylketonuria variant.

Brooks DL, Whittaker MN, Said H, Dwivedi G, Qu P, Musunuru K, Ahrens-Nicklas RC, Alameh MG, Wang X. Brooks DL, et al. HGG Adv. 2024 Jan 11;5(1):100253. doi: 10.1016/j.xhgg.2023.100253. Epub 2023 Nov 2. HGG Adv. 2024. PMID: 37922902 Free PMC article.

2

Detoxifying chemotherapy with genetics-guided stem cell modeling: A personalized affair.

Brooks DL, Musunuru K. Brooks DL, et al. Cell Stem Cell. 2021 Dec 2;28(12):2039-2040. doi: 10.1016/j.stem.2021.11.006. Cell Stem Cell. 2021. PMID: 34861143 Free article.

3

Rapid and definitive treatment of phenylketonuria in variant-humanized mice with corrective editing.

Brooks DL, Carrasco MJ, Qu P, Peranteau WH, Ahrens-Nicklas RC, Musunuru K, Alameh MG, Wang X. Brooks DL, et al. Nat Commun. 2023 Jun 10;14(1):3451. doi: 10.1038/s41467-023-39246-2. Nat Commun. 2023. PMID: 37301931 Free PMC article.

4

Efficient in vivo prime editing corrects the most frequent phenylketonuria variant, associated with high unmet medical need.

Brooks DL, Whittaker MN, Qu P, Musunuru K, Ahrens-Nicklas RC, Wang X. Brooks DL, et al. Am J Hum Genet. 2023 Dec 7;110(12):2003-2014. doi: 10.1016/j.ajhg.2023.10.005. Epub 2023 Nov 3. Am J Hum Genet. 2023. PMID: 37924808 Free PMC article.

5

Improved specificity and efficacy of base-editing therapies with hybrid guide RNAs.

Whittaker MN, Brooks DL, Quigley A, Jindal I, Qu P, Wang JZ, Ahrens-Nicklas RC, Musunuru K, Alameh MG, Peranteau WH, Wang X. Whittaker MN, et al. Among authors: brooks dl. bioRxiv [Preprint]. 2024 Apr 23:2024.04.22.590531. doi: 10.1101/2024.04.22.590531. bioRxiv. 2024. PMID: 38712058 Free PMC article. Preprint.

6

Response to Harding and Martinez.

Brooks DL, Musunuru K, Wang X. Brooks DL, et al. HGG Adv. 2024 May 14;5(3):100307. doi: 10.1016/j.xhgg.2024.100307. Online ahead of print. HGG Adv. 2024. PMID: 38796849 Free article. No abstract available.

7

Longitudinal changes in blood pressure are preceded by changes in albuminuria and accelerated by increasing dietary sodium intake.

Katayama IA, Huang Y, Garza AE, Brooks DL, Williams JS, Nascimento MM, Heimann JC, Pojoga LH. Katayama IA, et al. Among authors: brooks dl. Exp Gerontol. 2023 Mar;173:112114. doi: 10.1016/j.exger.2023.112114. Epub 2023 Feb 6. Exp Gerontol. 2023. PMID: 36738979 Free PMC article. Review.

8

Lysine-specific demethylase 1 deficiency modifies aldosterone synthesis in a sex-specific manner.

Tan YJD, Brooks DL, Wong KYH, Huang Y, Romero JR, Williams JS, Pojoga LH. Tan YJD, et al. Among authors: brooks dl. J Endocrinol. 2022 Dec 12;256(1):e220141. doi: 10.1530/JOE-22-0141. Print 2023 Jan 1. J Endocrinol. 2022. PMID: 36327153 Free PMC article.

9

Cardiovascular disease in women: A review of spontaneous coronary artery dissection.

Khiatah B, Jazayeri S, Yamamoto N, Burt T, Frugoli A, Brooks DL. Khiatah B, et al. Among authors: brooks dl. Medicine (Baltimore). 2022 Sep 23;101(38):e30433. doi: 10.1097/MD.0000000000030433. Medicine (Baltimore). 2022. PMID: 36197250 Free PMC article. Review.

10

HIF-Dependent CKB Expression Promotes Breast Cancer Metastasis, Whereas Cyclocreatine Therapy Impairs Cellular Invasion and Improves Chemotherapy Efficacy.

Krutilina RI, Playa H, Brooks DL, Schwab LP, Parke DN, Oluwalana D, Layman DR, Fan M, Johnson DL, Yue J, Smallwood H, Seagroves TN. Krutilina RI, et al. Among authors: brooks dl. Cancers (Basel). 2021 Dec 22;14(1):27. doi: 10.3390/cancers14010027. Cancers (Basel). 2021. PMID: 35008190 Free PMC article.

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