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The inhibition of inner mitochondrial fusion in hepatocytes reduces non-alcoholic fatty liver and improves metabolic profile during obesity by modulating bile acid conjugation.
Da Dalt L, Moregola A, Svecla M, Pedretti S, Fantini F, Ronzio M, Uboldi P, Dolfini D, Donetti E, Baragetti A, Mitro N, Scorrano L, Norata GD. Da Dalt L, et al. Among authors: scorrano l. Cardiovasc Res. 2024 Feb 17;119(18):2917-2929. doi: 10.1093/cvr/cvad169. Cardiovasc Res. 2024. PMID: 37922889
The mitochondrial protein Opa1 promotes adipocyte browning that is dependent on urea cycle metabolites.
Bean C, Audano M, Varanita T, Favaretto F, Medaglia M, Gerdol M, Pernas L, Stasi F, Giacomello M, Herkenne S, Muniandy M, Heinonen S, Cazaly E, Ollikainen M, Milan G, Pallavicini A, Pietiläinen KH, Vettor R, Mitro N, Scorrano L. Bean C, et al. Among authors: scorrano l. Nat Metab. 2021 Dec;3(12):1633-1647. doi: 10.1038/s42255-021-00497-2. Epub 2021 Dec 6. Nat Metab. 2021. PMID: 34873337 Free article.
Author Correction: The mitochondrial protein Opa1 promotes adipocyte browning that is dependent on urea cycle metabolites.
Bean C, Audano M, Varanita T, Favaretto F, Medaglia M, Gerdol M, Pernas L, Stasi F, Giacomello M, Herkenne S, Muniandy M, Heinonen S, Cazaly E, Ollikainen M, Milan G, Pallavicini A, Pietiläinen KH, Vettor R, Mitro N, Scorrano L. Bean C, et al. Among authors: scorrano l. Nat Metab. 2022 Feb;4(2):300. doi: 10.1038/s42255-022-00548-2. Nat Metab. 2022. PMID: 35149842 No abstract available.
Nitric oxide inhibition of Drp1-mediated mitochondrial fission is critical for myogenic differentiation.
De Palma C, Falcone S, Pisoni S, Cipolat S, Panzeri C, Pambianco S, Pisconti A, Allevi R, Bassi MT, Cossu G, Pozzan T, Moncada S, Scorrano L, Brunelli S, Clementi E. De Palma C, et al. Among authors: scorrano l. Cell Death Differ. 2010 Nov;17(11):1684-96. doi: 10.1038/cdd.2010.48. Epub 2010 May 14. Cell Death Differ. 2010. PMID: 20467441 Free PMC article.
Inhibition of the mitochondrial protein Opa1 curtails breast cancer growth.
Zamberlan M, Boeckx A, Muller F, Vinelli F, Ek O, Vianello C, Coart E, Shibata K, Christian A, Grespi F, Giacomello M, Struman I, Scorrano L, Herkenne S. Zamberlan M, et al. Among authors: scorrano l. J Exp Clin Cancer Res. 2022 Mar 12;41(1):95. doi: 10.1186/s13046-022-02304-6. J Exp Clin Cancer Res. 2022. PMID: 35279198 Free PMC article.
Shaping fuel utilization by mitochondria.
Alan L, Scorrano L. Alan L, et al. Among authors: scorrano l. Curr Biol. 2022 Jun 20;32(12):R618-R623. doi: 10.1016/j.cub.2022.05.006. Curr Biol. 2022. PMID: 35728541 Free article.
The cell biology of mitochondrial membrane dynamics.
Giacomello M, Pyakurel A, Glytsou C, Scorrano L. Giacomello M, et al. Among authors: scorrano l. Nat Rev Mol Cell Biol. 2020 Apr;21(4):204-224. doi: 10.1038/s41580-020-0210-7. Epub 2020 Feb 18. Nat Rev Mol Cell Biol. 2020. PMID: 32071438 Review.
RevAMPing Mitochondrial Shape to Live Longer.
Pernas L, Scorrano L. Pernas L, et al. Among authors: scorrano l. Cell Metab. 2017 Dec 5;26(6):805-806. doi: 10.1016/j.cmet.2017.11.010. Cell Metab. 2017. PMID: 29211978 Free article.
Orchestration of lymphocyte chemotaxis by mitochondrial dynamics.
Campello S, Lacalle RA, Bettella M, Mañes S, Scorrano L, Viola A. Campello S, et al. Among authors: scorrano l. J Exp Med. 2006 Dec 25;203(13):2879-86. doi: 10.1084/jem.20061877. Epub 2006 Dec 4. J Exp Med. 2006. PMID: 17145957 Free PMC article.
213 results