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Covalent Peptide LSD1 Inhibitor Specifically Recognizes Cys360 in the Enzyme-Active Region.
Luo Q, Ma Y, Liang H, Feng Y, Liu N, Lian C, Zhu L, Ye Y, Liu Z, Hou Z, Chen S, Wang Y, Dai C, Song C, Zhang M, He Z, Xing Y, Zhong W, Li S, Wu J, Lu F, Yin F, Li Z. Luo Q, et al. Among authors: zhu l. J Med Chem. 2023 Nov 23;66(22):15409-15423. doi: 10.1021/acs.jmedchem.3c01549. Epub 2023 Nov 3. J Med Chem. 2023. PMID: 37922441
Targeted Biomolecule Regulation Platform: A Split-and-Mix PROTAC Approach.
Yang F, Luo Q, Wang Y, Liang H, Wang Y, Hou Z, Wan C, Wang Y, Liu Z, Ye Y, Zhu L, Wu J, Yin F, Li Z. Yang F, et al. Among authors: zhu l. J Am Chem Soc. 2023 Apr 12;145(14):7879-7887. doi: 10.1021/jacs.2c12824. Epub 2023 Mar 31. J Am Chem Soc. 2023. PMID: 37001133
Covalent PROTAC design method based on a sulfonyl pyridone probe.
Luo Q, Wang Y, Hou Z, Liang H, Tu L, Xing Y, Wan C, Liu J, Wang R, Zhu L, Han W, Wu J, Lu F, Yin F, Li Z. Luo Q, et al. Among authors: zhu l. Chem Commun (Camb). 2024 Jan 16;60(6):686-689. doi: 10.1039/d3cc05127g. Chem Commun (Camb). 2024. PMID: 38054347
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