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Monomeric α-synuclein activates the plasma membrane calcium pump.
Kowalski A, Betzer C, Larsen ST, Gregersen E, Newcombe EA, Bermejo MC, Bendtsen VW, Diemer J, Ernstsen CV, Jain S, Bou AE, Langkilde AE, Nejsum LN, Klipp E, Edwards R, Kragelund BB, Jensen PH, Nissen P. Kowalski A, et al. Among authors: jensen ph. EMBO J. 2023 Dec 1;42(23):e111122. doi: 10.15252/embj.2022111122. Epub 2023 Nov 2. EMBO J. 2023. PMID: 37916890 Free PMC article.
How epigallocatechin gallate can inhibit α-synuclein oligomer toxicity in vitro.
Lorenzen N, Nielsen SB, Yoshimura Y, Vad BS, Andersen CB, Betzer C, Kaspersen JD, Christiansen G, Pedersen JS, Jensen PH, Mulder FA, Otzen DE. Lorenzen N, et al. Among authors: jensen ph. J Biol Chem. 2014 Aug 1;289(31):21299-310. doi: 10.1074/jbc.M114.554667. Epub 2014 Jun 6. J Biol Chem. 2014. PMID: 24907278 Free PMC article.
Protein Partners of α-Synuclein in Health and Disease.
Lassen LB, Reimer L, Ferreira N, Betzer C, Jensen PH. Lassen LB, et al. Among authors: jensen ph. Brain Pathol. 2016 May;26(3):389-97. doi: 10.1111/bpa.12374. Brain Pathol. 2016. PMID: 26940507 Free PMC article. Review.
Alpha-synuclein aggregates activate calcium pump SERCA leading to calcium dysregulation.
Betzer C, Lassen LB, Olsen A, Kofoed RH, Reimer L, Gregersen E, Zheng J, Calì T, Gai WP, Chen T, Moeller A, Brini M, Fu Y, Halliday G, Brudek T, Aznar S, Pakkenberg B, Andersen JP, Jensen PH. Betzer C, et al. Among authors: jensen ph. EMBO Rep. 2018 May;19(5):e44617. doi: 10.15252/embr.201744617. Epub 2018 Mar 29. EMBO Rep. 2018. PMID: 29599149 Free PMC article.
217 results