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First-in-human phase I/Ib study of NIZ985, a recombinant heterodimer of IL-15 and IL-15Rα, as a single agent and in combination with spartalizumab in patients with advanced and metastatic solid tumors.
J Immunother Cancer. 2023 Oct;11(10):e007725. doi: 10.1136/jitc-2023-007725.
J Immunother Cancer. 2023.
PMID: 37907221
Free PMC article.
Clinical Trial.
Identification and characterization of an alternative cancer-derived PD-L1 splice variant.
Hassounah NB, Malladi VS, Huang Y, Freeman SS, Beauchamp EM, Koyama S, Souders N, Martin S, Dranoff G, Wong KK, Pedamallu CS, Hammerman PS, Akbay EA.
Hassounah NB, et al.
Cancer Immunol Immunother. 2019 Mar;68(3):407-420. doi: 10.1007/s00262-018-2284-z. Epub 2018 Dec 18.
Cancer Immunol Immunother. 2019.
PMID: 30564890
Free PMC article.
Item in Clipboard
Inhibition of Ciliogenesis Promotes Hedgehog Signaling, Tumorigenesis, and Metastasis in Breast Cancer.
Hassounah NB, Nunez M, Fordyce C, Roe D, Nagle R, Bunch T, McDermott KM.
Hassounah NB, et al.
Mol Cancer Res. 2017 Oct;15(10):1421-1430. doi: 10.1158/1541-7786.MCR-17-0034. Epub 2017 Jun 13.
Mol Cancer Res. 2017.
PMID: 28611083
Free PMC article.
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Loss of primary cilia occurs early in breast cancer development.
Menzl I, Lebeau L, Pandey R, Hassounah NB, Li FW, Nagle R, Weihs K, McDermott KM.
Menzl I, et al. Among authors: hassounah nb.
Cilia. 2014 Jul 1;3:7. doi: 10.1186/2046-2530-3-7. eCollection 2014.
Cilia. 2014.
PMID: 24987519
Free PMC article.
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Primary cilia are lost in preinvasive and invasive prostate cancer.
Hassounah NB, Nagle R, Saboda K, Roe DJ, Dalkin BL, McDermott KM.
Hassounah NB, et al.
PLoS One. 2013 Jul 2;8(7):e68521. doi: 10.1371/journal.pone.0068521. Print 2013.
PLoS One. 2013.
PMID: 23844214
Free PMC article.
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Molecular pathways: the role of primary cilia in cancer progression and therapeutics with a focus on Hedgehog signaling.
Hassounah NB, Bunch TA, McDermott KM.
Hassounah NB, et al.
Clin Cancer Res. 2012 May 1;18(9):2429-35. doi: 10.1158/1078-0432.CCR-11-0755. Epub 2012 Mar 13.
Clin Cancer Res. 2012.
PMID: 22415315
Free PMC article.
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Cancer and age related colonic crypt deficiencies in cytochrome c oxidase I.
Bernstein C, Facista A, Nguyen H, Zaitlin B, Hassounah N, Loustaunau C, Payne CM, Banerjee B, Goldschmid S, Tsikitis VL, Krouse R, Bernstein H.
Bernstein C, et al. Among authors: hassounah n.
World J Gastrointest Oncol. 2010 Dec 15;2(12):429-42. doi: 10.4251/wjgo.v2.i12.429.
World J Gastrointest Oncol. 2010.
PMID: 21191537
Free PMC article.
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Deficient Pms2, ERCC1, Ku86, CcOI in field defects during progression to colon cancer.
Nguyen H, Loustaunau C, Facista A, Ramsey L, Hassounah N, Taylor H, Krouse R, Payne CM, Tsikitis VL, Goldschmid S, Banerjee B, Perini RF, Bernstein C.
Nguyen H, et al. Among authors: hassounah n.
J Vis Exp. 2010 Jul 28;(41):1931. doi: 10.3791/1931.
J Vis Exp. 2010.
PMID: 20689513
Free PMC article.
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