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LKB1 suppresses growth and promotes the internalization of EGFR through the PIKFYVE lipid kinase.
Ferrarone JR, Thomas J, Unni AM, Zheng Y, Nagiec MJ, Gardner EE, Mashadova O, Li K, Koundouros N, Montalbano A, Mustafa M, Cantley LC, Blenis J, Sanjana NE, Varmus H. Ferrarone JR, et al. Among authors: sanjana ne. bioRxiv [Preprint]. 2023 Oct 20:2023.10.19.563158. doi: 10.1101/2023.10.19.563158. bioRxiv. 2023. PMID: 37904985 Free PMC article. Preprint.
Low copy CRISPR-Cas13d mitigates collateral RNA cleavage.
Hart SK, Wessels HH, Méndez-Mancilla A, Müller S, Drabavicius G, Choi O, Sanjana NE. Hart SK, et al. Among authors: sanjana ne. bioRxiv [Preprint]. 2024 May 14:2024.05.13.594039. doi: 10.1101/2024.05.13.594039. bioRxiv. 2024. PMID: 38798586 Free PMC article. Preprint.
Genome-wide CRISPR screens in spheroid culture reveal that the tumor suppressor LKB1 inhibits growth via the PIKFYVE lipid kinase.
Ferrarone JR, Thomas J, Unni AM, Zheng Y, Nagiec MJ, Gardner EE, Mashadova O, Li K, Koundouros N, Montalbano A, Mustafa M, Cantley LC, Blenis J, Sanjana NE, Varmus H. Ferrarone JR, et al. Among authors: sanjana ne. Proc Natl Acad Sci U S A. 2024 May 21;121(21):e2403685121. doi: 10.1073/pnas.2403685121. Epub 2024 May 14. Proc Natl Acad Sci U S A. 2024. PMID: 38743625 Free PMC article.
Essential transcription factors for induced neuron differentiation.
Lu C, Garipler G, Dai C, Roush T, Salome-Correa J, Martin A, Liscovitch-Brauer N, Mazzoni EO, Sanjana NE. Lu C, et al. Among authors: sanjana ne. Nat Commun. 2023 Dec 15;14(1):8362. doi: 10.1038/s41467-023-43602-7. Nat Commun. 2023. PMID: 38102126 Free PMC article.
74 results