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Proteomics reveal biomarkers for diagnosis, disease activity and long-term disability outcomes in multiple sclerosis.
Åkesson J, Hojjati S, Hellberg S, Raffetseder J, Khademi M, Rynkowski R, Kockum I, Altafini C, Lubovac-Pilav Z, Mellergård J, Jenmalm MC, Piehl F, Olsson T, Ernerudh J, Gustafsson M. Åkesson J, et al. Among authors: hellberg s. Nat Commun. 2023 Oct 30;14(1):6903. doi: 10.1038/s41467-023-42682-9. Nat Commun. 2023. PMID: 37903821 Free PMC article.
Dynamic Response Genes in CD4+ T Cells Reveal a Network of Interactive Proteins that Classifies Disease Activity in Multiple Sclerosis.
Hellberg S, Eklund D, Gawel DR, Köpsén M, Zhang H, Nestor CE, Kockum I, Olsson T, Skogh T, Kastbom A, Sjöwall C, Vrethem M, Håkansson I, Benson M, Jenmalm MC, Gustafsson M, Ernerudh J. Hellberg S, et al. Cell Rep. 2016 Sep 13;16(11):2928-2939. doi: 10.1016/j.celrep.2016.08.036. Cell Rep. 2016. PMID: 27626663 Free article.
Plasma protein profiling reveals dynamic immunomodulatory changes in multiple sclerosis patients during pregnancy.
Papapavlou Lingehed G, Hellberg S, Huang J, Khademi M, Kockum I, Carlsson H, Tjernberg I, Svenvik M, Lind J, Blomberg M, Vrethem M, Mellergård J, Gustafsson M, Jenmalm MC, Olsson T, Ernerudh J. Papapavlou Lingehed G, et al. Among authors: hellberg s. Front Immunol. 2022 Jul 29;13:930947. doi: 10.3389/fimmu.2022.930947. eCollection 2022. Front Immunol. 2022. PMID: 35967338 Free PMC article.
Prominent epigenetic and transcriptomic changes in CD4+ and CD8+ T cells during and after pregnancy in women with multiple sclerosis and controls.
Zenere A, Hellberg S, Papapavlou Lingehed G, Svenvik M, Mellergård J, Dahle C, Vrethem M, Raffetseder J, Khademi M, Olsson T, Blomberg M, Jenmalm MC, Altafini C, Gustafsson M, Ernerudh J. Zenere A, et al. Among authors: hellberg s. J Neuroinflammation. 2023 Apr 27;20(1):98. doi: 10.1186/s12974-023-02781-2. J Neuroinflammation. 2023. PMID: 37106402 Free PMC article.
RNA-sequencing and mass-spectrometry proteomic time-series analysis of T-cell differentiation identified multiple splice variants models that predicted validated protein biomarkers in inflammatory diseases.
Magnusson R, Rundquist O, Kim MJ, Hellberg S, Na CH, Benson M, Gomez-Cabrero D, Kockum I, Tegnér JN, Piehl F, Jagodic M, Mellergård J, Altafini C, Ernerudh J, Jenmalm MC, Nestor CE, Kim MS, Gustafsson M. Magnusson R, et al. Among authors: hellberg s. Front Mol Biosci. 2022 Aug 29;9:916128. doi: 10.3389/fmolb.2022.916128. eCollection 2022. Front Mol Biosci. 2022. PMID: 36106020 Free PMC article.
A validated gene regulatory network and GWAS identifies early regulators of T cell-associated diseases.
Gustafsson M, Gawel DR, Alfredsson L, Baranzini S, Björkander J, Blomgran R, Hellberg S, Eklund D, Ernerudh J, Kockum I, Konstantinell A, Lahesmaa R, Lentini A, Liljenström HR, Mattson L, Matussek A, Mellergård J, Mendez M, Olsson T, Pujana MA, Rasool O, Serra-Musach J, Stenmarker M, Tripathi S, Viitala M, Wang H, Zhang H, Nestor CE, Benson M. Gustafsson M, et al. Among authors: hellberg s. Sci Transl Med. 2015 Nov 11;7(313):313ra178. doi: 10.1126/scitranslmed.aad2722. Sci Transl Med. 2015. PMID: 26560356 Free article.
CD4+ T-cell DNA methylation changes during pregnancy significantly correlate with disease-associated methylation changes in autoimmune diseases.
Badam TV, Hellberg S, Mehta RB, Lechner-Scott J, Lea RA, Tost J, Mariette X, Svensson-Arvelund J, Nestor CE, Benson M, Berg G, Jenmalm MC, Gustafsson M, Ernerudh J. Badam TV, et al. Among authors: hellberg s. Epigenetics. 2022 Sep;17(9):1040-1055. doi: 10.1080/15592294.2021.1982510. Epub 2021 Oct 4. Epigenetics. 2022. PMID: 34605719 Free PMC article.
95 results