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Conditional Deletion of Pdcd1 Identifies the Cell-Intrinsic Action of PD-1 on Functional CD8 T Cell Subsets for Antitumor Efficacy.
Raghavan S, Tovbis-Shifrin N, Kochel C, Sawant A, Mello M, Sathe M, Blumenschein W, Muise ES, Chackerian A, Pinheiro EM, Rosahl TW, Luche H, de Waal Malefyt R. Raghavan S, et al. Among authors: luche h. Front Immunol. 2021 Nov 29;12:752348. doi: 10.3389/fimmu.2021.752348. eCollection 2021. Front Immunol. 2021. PMID: 34912335 Free PMC article.
Fate mapping analysis of lymphoid cells expressing the NKp46 cell surface receptor.
Narni-Mancinelli E, Chaix J, Fenis A, Kerdiles YM, Yessaad N, Reynders A, Gregoire C, Luche H, Ugolini S, Tomasello E, Walzer T, Vivier E. Narni-Mancinelli E, et al. Among authors: luche h. Proc Natl Acad Sci U S A. 2011 Nov 8;108(45):18324-9. doi: 10.1073/pnas.1112064108. Epub 2011 Oct 21. Proc Natl Acad Sci U S A. 2011. PMID: 22021440 Free PMC article.
Cytomegalovirus Infection of the Rat Developing Brain In Utero Prominently Targets Immune Cells and Promotes Early Microglial Activation.
Cloarec R, Bauer S, Luche H, Buhler E, Pallesi-Pocachard E, Salmi M, Courtens S, Massacrier A, Grenot P, Teissier N, Watrin F, Schaller F, Adle-Biassette H, Gressens P, Malissen M, Stamminger T, Streblow DN, Bruneau N, Szepetowski P. Cloarec R, et al. Among authors: luche h. PLoS One. 2016 Jul 29;11(7):e0160176. doi: 10.1371/journal.pone.0160176. eCollection 2016. PLoS One. 2016. PMID: 27472761 Free PMC article.
Anti-HVEM mAb therapy improves antitumoral immunity both in vitro and in vivo, in a novel transgenic mouse model expressing human HVEM and BTLA molecules challenged with HVEM expressing tumors.
Demerlé C, Gorvel L, Mello M, Pastor S, Degos C, Zarubica A, Angelis F, Fiore F, Nunes JA, Malissen B, Greillier L, Guittard G, Luche H, Barlesi F, Olive D. Demerlé C, et al. Among authors: luche h. J Immunother Cancer. 2023 May;11(5):e006348. doi: 10.1136/jitc-2022-006348. J Immunother Cancer. 2023. PMID: 37230538 Free PMC article.
CD5L as a promising biological therapeutic for treating sepsis.
Oliveira L, Silva MC, Gomes AP, Santos RF, Cardoso MS, Nóvoa A, Luche H, Cavadas B, Amorim I, Gärtner F, Malissen B, Mallo M, Carmo AM. Oliveira L, et al. Among authors: luche h. Nat Commun. 2024 May 15;15(1):4119. doi: 10.1038/s41467-024-48360-8. Nat Commun. 2024. PMID: 38750020 Free PMC article.
Natural Killer Defective Maturation Is Associated with Adverse Clinical Outcome in Patients with Acute Myeloid Leukemia.
Chretien AS, Fauriat C, Orlanducci F, Galseran C, Rey J, Bouvier Borg G, Gautherot E, Granjeaud S, Hamel-Broza JF, Demerle C, Ifrah N, Lacombe C, Cornillet-Lefebvre P, Delaunay J, Toubert A, Gregori E, Luche H, Malissen M, Arnoulet C, Nunes JA, Vey N, Olive D. Chretien AS, et al. Among authors: luche h. Front Immunol. 2017 May 29;8:573. doi: 10.3389/fimmu.2017.00573. eCollection 2017. Front Immunol. 2017. PMID: 28611767 Free PMC article.
Atp6ap2 ablation in adult mice impairs viability through multiple organ deficiencies.
Wendling O, Champy MF, Jaubert S, Pavlovic G, Dubos A, Lindner L, Jacobs H, Mark M, Combe R, Da Cruz IG, Luche H, Mudgett JS, Rosahl T, Sorg T, Malissen M, Reilly PT, Hérault Y. Wendling O, et al. Among authors: luche h. Sci Rep. 2017 Aug 29;7(1):9618. doi: 10.1038/s41598-017-08845-7. Sci Rep. 2017. PMID: 28851918 Free PMC article.
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