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Platelet collagen receptor Glycoprotein VI-dimer recognizes fibrinogen and fibrin through their D-domains, contributing to platelet adhesion and activation during thrombus formation.
Induruwa I, Moroi M, Bonna A, Malcor JD, Howes JM, Warburton EA, Farndale RW, Jung SM. Induruwa I, et al. Among authors: farndale rw. J Thromb Haemost. 2018 Feb;16(2):389-404. doi: 10.1111/jth.13919. Epub 2018 Jan 15. J Thromb Haemost. 2018. PMID: 29210180 Free PMC article.
Multimerin 1 supports platelet function in vivo and binds to specific GPAGPOGPX motifs in fibrillar collagens that enhance platelet adhesion.
Leatherdale A, Parker D, Tasneem S, Wang Y, Bihan D, Bonna A, Hamaia SW, Gross PL, Ni H, Doble BW, Lillicrap D, Farndale RW, Hayward CPM. Leatherdale A, et al. Among authors: farndale rw. J Thromb Haemost. 2021 Feb;19(2):547-561. doi: 10.1111/jth.15171. Epub 2020 Dec 17. J Thromb Haemost. 2021. PMID: 33179420 Free PMC article.
Platelet surface receptor glycoprotein VI-dimer is overexpressed in stroke: The Glycoprotein VI in Stroke (GYPSIE) study results.
Induruwa I, McKinney H, Kempster C, Thomas P, Batista J, Malcor JD, Bonna A, McGee J, Bumanlag-Amis E, Rehnstrom K, Ashford S, Soejima K, Ouwehand W, Farndale R, Downes K, Warburton E, Moroi M, Jung S. Induruwa I, et al. PLoS One. 2022 Jan 18;17(1):e0262695. doi: 10.1371/journal.pone.0262695. eCollection 2022. PLoS One. 2022. PMID: 35041713 Free PMC article.
Tyrosine-sulfated dermatopontin shares multiple binding sites and recognition determinants on triple-helical collagens with proteins implicated in cell adhesion and collagen folding, fibrillogenesis, cross-linking, and degradation.
Jensen MM, Bonna A, Frederiksen SJ, Hamaia SW, Højrup P, Farndale RW, Karring H. Jensen MM, et al. Among authors: farndale rw. Biochim Biophys Acta Proteins Proteom. 2022 May 1;1870(5):140771. doi: 10.1016/j.bbapap.2022.140771. Epub 2022 Mar 16. Biochim Biophys Acta Proteins Proteom. 2022. PMID: 35306228 Free article.
Platelet Receptor Glycoprotein VI-Dimer Is Overexpressed in Patients with Atrial Fibrillation at High Risk of Ischemic Stroke.
Induruwa I, Kempster C, Thomas P, McKinney H, Malcor JD, Bonna A, Batista J, Soejima K, Ouwehand W, Farndale RW, Downes K, Moroi M, Jung SM, Warburton EA. Induruwa I, et al. Among authors: farndale rw. TH Open. 2023 Nov 13;7(4):e294-e302. doi: 10.1055/s-0043-1776328. eCollection 2023 Oct. TH Open. 2023. PMID: 37964899 Free PMC article.
226 results