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G Protein-Coupled Receptor Kinase 2 Selectively Enhances β-Arrestin Recruitment to the D2 Dopamine Receptor through Mechanisms That Are Independent of Receptor Phosphorylation.
Sánchez-Soto M, Boldizsar NM, Schardien KA, Madaras NS, Willette BKA, Inbody LR, Dasaro C, Moritz AE, Drube J, Haider RS, Free RB, Hoffman C, Sibley DR. Sánchez-Soto M, et al. Among authors: sibley dr. Biomolecules. 2023 Oct 20;13(10):1552. doi: 10.3390/biom13101552. Biomolecules. 2023. PMID: 37892234 Free PMC article.
[No title available]
[No authors listed] [No authors listed] PMID: 35567436
Structure-Activity Investigation of a G Protein-Biased Agonist Reveals Molecular Determinants for Biased Signaling of the D2 Dopamine Receptor.
Chun LS, Vekariya RH, Free RB, Li Y, Lin DT, Su P, Liu F, Namkung Y, Laporte SA, Moritz AE, Aubé J, Frankowski KJ, Sibley DR. Chun LS, et al. Among authors: sibley dr. Front Synaptic Neurosci. 2018 Feb 21;10:2. doi: 10.3389/fnsyn.2018.00002. eCollection 2018. Front Synaptic Neurosci. 2018. PMID: 29515433 Free PMC article.
Pharmacological Characterization of the Imipridone Anticancer Drug ONC201 Reveals a Negative Allosteric Mechanism of Action at the D2 Dopamine Receptor.
Free RB, Cuoco CA, Xie B, Namkung Y, Prabhu VV, Willette BKA, Day MM, Sanchez-Soto M, Lane JR, Laporte SA, Shi L, Allen JE, Sibley DR. Free RB, et al. Among authors: sibley dr. Mol Pharmacol. 2021 Oct;100(4):372-387. doi: 10.1124/molpharm.121.000336. Epub 2021 Aug 5. Mol Pharmacol. 2021. PMID: 34353882 Free PMC article.
228 results