Bolleddula J - Search Results

1

Implementation of whole-exome sequencing for pharmacogenomics profiling and exploring its potential clinical utilities.

Wang D, Bolleddula J, Coenen-Stass A, Grombacher T, Dong JQ, Scheuenpflug J, Locatelli G, Feng Z. Wang D, et al. Among authors: bolleddula j. Pharmacogenomics. 2024 Mar;25(4):197-206. doi: 10.2217/pgs-2023-0243. Epub 2024 Mar 21. Pharmacogenomics. 2024. PMID: 38511470 Free article.

2

A Case to Support the Continued Use of Rifampin in Clinical Drug-Drug Interaction Studies.

Bercu JP, Ponting DJ, Ripp SL, Dobo KL, Totah RA, Bolleddula J. Bercu JP, et al. Among authors: bolleddula j. Clin Pharmacol Ther. 2024 Mar 18. doi: 10.1002/cpt.3256. Online ahead of print. Clin Pharmacol Ther. 2024. PMID: 38494918 No abstract available.

3

A phase I study of ATR inhibitor gartisertib (M4344) as a single agent and in combination with carboplatin in patients with advanced solid tumours.

Burris HA, Berlin J, Arkenau T, Cote GM, Lolkema MP, Ferrer-Playan J, Kalapur A, Bolleddula J, Locatelli G, Goddemeier T, Gounaris I, de Bono J. Burris HA, et al. Among authors: bolleddula j. Br J Cancer. 2024 Apr;130(7):1131-1140. doi: 10.1038/s41416-023-02436-2. Epub 2024 Jan 29. Br J Cancer. 2024. PMID: 38287179 Free PMC article. Clinical Trial.

4

Evobrutinib pathway to its major metabolite M463-2 and insights from a biotransformation and DDI perspective.

Scheible H, Schieferstein H, Schmidt R, Pusecker K, Gradhand U, Gopalakrishnan S, Iqbal K, Dong J, Jones R, Meli C, Bolleddula J, Dyroff M, Georgi K. Scheible H, et al. Among authors: bolleddula j. Xenobiotica. 2023 Dec;53(8-9):547-558. doi: 10.1080/00498254.2023.2272180. Epub 2023 Nov 26. Xenobiotica. 2023. PMID: 37880944

5

Challenges and Opportunities for In Vitro-In Vivo Extrapolation of Aldehyde Oxidase-Mediated Clearance: Toward a Roadmap for Quantitative Translation.

Izat N, Bolleddula J, Abbasi A, Cheruzel L, Jones RS, Moss D, Ortega-Muro F, Parmentier Y, Peterkin VC, Tian DD, Venkatakrishnan K, Zientek MA, Barber J, Houston JB, Galetin A, Scotcher D. Izat N, et al. Among authors: bolleddula j. Drug Metab Dispos. 2023 Dec;51(12):1591-1606. doi: 10.1124/dmd.123.001436. Epub 2023 Sep 26. Drug Metab Dispos. 2023. PMID: 37751998

6

No person left behind: Mapping the health policy landscape for genomics research in the Caribbean.

Bolleddula J, Simeon D, Anderson SG, Shields L, Mullings J, Ossorio P, Bethelmey A, Perkins AK. Bolleddula J, et al. Lancet Reg Health Am. 2022 Sep 18;15:100367. doi: 10.1016/j.lana.2022.100367. eCollection 2022 Nov. Lancet Reg Health Am. 2022. PMID: 36778076 Free PMC article. Review.

7

Alternatives to rifampicin: A review and perspectives on the choice of strong CYP3A inducers for clinical drug-drug interaction studies.

Bolleddula J, Gopalakrishnan S, Hu P, Dong J, Venkatakrishnan K. Bolleddula J, et al. Clin Transl Sci. 2022 Sep;15(9):2075-2095. doi: 10.1111/cts.13357. Epub 2022 Jul 25. Clin Transl Sci. 2022. PMID: 35722783 Free PMC article. Review.

8

Metabolism and Disposition of [¹⁴C]Pevonedistat, a First-in-Class NEDD8-Activating Enzyme Inhibitor, after Intravenous Infusion to Patients with Advanced Solid Tumors.

Bolleddula J, Chen H, Cohen L, Zhou X, Pusalkar S, Berger A, Sedarati F, Venkatakrishnan K, Chowdhury SK. Bolleddula J, et al. Drug Metab Dispos. 2022 Jul;50(7):989-997. doi: 10.1124/dmd.122.000842. Epub 2022 May 3. Drug Metab Dispos. 2022. PMID: 35504658

9

Absorption, Distribution, Metabolism, and Excretion of Therapeutic Proteins: Current Industry Practices and Future Perspectives.

Bolleddula J, Brady K, Bruin G, Lee A, Martin JA, Walles M, Xu K, Yang TY, Zhu X, Yu H. Bolleddula J, et al. Drug Metab Dispos. 2022 Jun;50(6):837-845. doi: 10.1124/dmd.121.000461. Epub 2022 Feb 11. Drug Metab Dispos. 2022. PMID: 35149541

10

Current Practices, Gap Analysis, and Proposed Workflows for PBPK Modeling of Cytochrome P450 Induction: An Industry Perspective.

Hariparsad N, Ramsden D, Taskar K, Badée J, Venkatakrishnan K, Reddy MB, Cabalu T, Mukherjee D, Rehmel J, Bolleddula J, Emami Riedmaier A, Prakash C, Chanteux H, Mao J, Umehara K, Shah K, De Zwart L, Dowty M, Kotsuma M, Li M, Pilla Reddy V, McGinnity DF, Parrott N. Hariparsad N, et al. Among authors: bolleddula j. Clin Pharmacol Ther. 2022 Oct;112(4):770-781. doi: 10.1002/cpt.2503. Epub 2021 Dec 24. Clin Pharmacol Ther. 2022. PMID: 34862964

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