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CXCL10 deficiency limits macrophage infiltration, preserves lung matrix, and enables lung growth in bronchopulmonary dysplasia.
Hirani DV, Thielen F, Mansouri S, Danopoulos S, Vohlen C, Haznedar-Karakaya P, Mohr J, Wilke R, Selle J, Grosch T, Mizik I, Odenthal M, Alvira CM, Kuiper-Makris C, Pryhuber GS, Pallasch C, van Koningsbruggen-Rietschel S, Al-Alam D, Seeger W, Savai R, Dötsch J, Alejandre Alcazar MA. Hirani DV, et al. Among authors: alvira cm. Inflamm Regen. 2023 Oct 24;43(1):52. doi: 10.1186/s41232-023-00301-6. Inflamm Regen. 2023. PMID: 37876024 Free PMC article.
Macrophage-derived IL-6 trans-signalling as a novel target in the pathogenesis of bronchopulmonary dysplasia.
Hirani D, Alvira CM, Danopoulos S, Milla C, Donato M, Tian L, Mohr J, Dinger K, Vohlen C, Selle J, V Koningsbruggen-Rietschel S, Barbarino V, Pallasch C, Rose-John S, Odenthal M, Pryhuber GS, Mansouri S, Savai R, Seeger W, Khatri P, Al Alam D, Dötsch J, Alejandre Alcazar MA. Hirani D, et al. Among authors: alvira cm. Eur Respir J. 2022 Feb 17;59(2):2002248. doi: 10.1183/13993003.02248-2020. Print 2022 Feb. Eur Respir J. 2022. PMID: 34446466 Free PMC article.
Inhibiting NF-κB in the developing lung disrupts angiogenesis and alveolarization.
Iosef C, Alastalo TP, Hou Y, Chen C, Adams ES, Lyu SC, Cornfield DN, Alvira CM. Iosef C, et al. Among authors: alvira cm. Am J Physiol Lung Cell Mol Physiol. 2012 May 15;302(10):L1023-36. doi: 10.1152/ajplung.00230.2011. Epub 2012 Feb 24. Am J Physiol Lung Cell Mol Physiol. 2012. PMID: 22367785 Free PMC article.
Activation of the nuclear factor-κB pathway during postnatal lung inflammation preserves alveolarization by suppressing macrophage inflammatory protein-2.
Hou Y, Liu M, Husted C, Chen C, Thiagarajan K, Johns JL, Rao SP, Alvira CM. Hou Y, et al. Among authors: alvira cm. Am J Physiol Lung Cell Mol Physiol. 2015 Sep 15;309(6):L593-604. doi: 10.1152/ajplung.00029.2015. Epub 2015 Jul 10. Am J Physiol Lung Cell Mol Physiol. 2015. PMID: 26163511 Free PMC article.
48 results