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Structure and Dynamics Guiding Design of Antibody Therapeutics and Vaccines.
Fernández-Quintero ML, Pomarici ND, Fischer AM, Hoerschinger VJ, Kroell KB, Riccabona JR, Kamenik AS, Loeffler JR, Ferguson JA, Perrett HR, Liedl KR, Han J, Ward AB. Fernández-Quintero ML, et al. Among authors: ward ab. Antibodies (Basel). 2023 Oct 18;12(4):67. doi: 10.3390/antib12040067. Antibodies (Basel). 2023. PMID: 37873864 Free PMC article. Review.
A cross-neutralizing antibody between HIV-1 and influenza virus.
Lee CD, Watanabe Y, Wu NC, Han J, Kumar S, Pholcharee T, Seabright GE, Allen JD, Lin CW, Yang JR, Liu MT, Wu CY, Ward AB, Crispin M, Wilson IA. Lee CD, et al. Among authors: ward ab. PLoS Pathog. 2021 Mar 22;17(3):e1009407. doi: 10.1371/journal.ppat.1009407. eCollection 2021 Mar. PLoS Pathog. 2021. PMID: 33750987 Free PMC article.
Polyclonal antibody responses to HIV Env immunogens resolved using cryoEM.
Antanasijevic A, Sewall LM, Cottrell CA, Carnathan DG, Jimenez LE, Ngo JT, Silverman JB, Groschel B, Georgeson E, Bhiman J, Bastidas R, LaBranche C, Allen JD, Copps J, Perrett HR, Rantalainen K, Cannac F, Yang YR, de la Peña AT, Rocha RF, Berndsen ZT, Baker D, King NP, Sanders RW, Moore JP, Crotty S, Crispin M, Montefiori DC, Burton DR, Schief WR, Silvestri G, Ward AB. Antanasijevic A, et al. Among authors: ward ab. Nat Commun. 2021 Aug 10;12(1):4817. doi: 10.1038/s41467-021-25087-4. Nat Commun. 2021. PMID: 34376662 Free PMC article.
Broadly neutralizing antibodies target a haemagglutinin anchor epitope.
Guthmiller JJ, Han J, Utset HA, Li L, Lan LY, Henry C, Stamper CT, McMahon M, O'Dell G, Fernández-Quintero ML, Freyn AW, Amanat F, Stovicek O, Gentles L, Richey ST, de la Peña AT, Rosado V, Dugan HL, Zheng NY, Tepora ME, Bitar DJ, Changrob S, Strohmeier S, Huang M, García-Sastre A, Liedl KR, Bloom JD, Nachbagauer R, Palese P, Krammer F, Coughlan L, Ward AB, Wilson PC. Guthmiller JJ, et al. Among authors: ward ab. Nature. 2022 Feb;602(7896):314-320. doi: 10.1038/s41586-021-04356-8. Epub 2021 Dec 23. Nature. 2022. PMID: 34942633 Free PMC article.
Lassa virus glycoprotein nanoparticles elicit neutralizing antibody responses and protection.
Brouwer PJM, Antanasijevic A, Ronk AJ, Müller-Kräuter H, Watanabe Y, Claireaux M, Perrett HR, Bijl TPL, Grobben M, Umotoy JC, Schriek AI, Burger JA, Tejjani K, Lloyd NM, Steijaert TH, van Haaren MM, Sliepen K, de Taeye SW, van Gils MJ, Crispin M, Strecker T, Bukreyev A, Ward AB, Sanders RW. Brouwer PJM, et al. Among authors: ward ab. Cell Host Microbe. 2022 Dec 14;30(12):1759-1772.e12. doi: 10.1016/j.chom.2022.10.018. Epub 2022 Nov 17. Cell Host Microbe. 2022. PMID: 36400021 Free PMC article.
A Lassa virus mRNA vaccine confers protection but does not require neutralizing antibody in a guinea pig model of infection.
Ronk AJ, Lloyd NM, Zhang M, Atyeo C, Perrett HR, Mire CE, Hastie KM, Sanders RW, Brouwer PJM, Saphire EO, Ward AB, Ksiazek TG, Alvarez Moreno JC, Thaker HM, Alter G, Himansu S, Carfi A, Bukreyev A. Ronk AJ, et al. Among authors: ward ab. Nat Commun. 2023 Sep 12;14(1):5603. doi: 10.1038/s41467-023-41376-6. Nat Commun. 2023. PMID: 37699929 Free PMC article.
Immune memory shapes human polyclonal antibody responses to H2N2 vaccination.
Yang YR, Han J, Perrett HR, Richey ST, Jackson AM, Rodriguez AJ, Gillespie RA, O'Connell S, Raab JE, Cominsky LY, Chopde A, Kanekiyo M, Houser KV, Chen GL, McDermott AB, Andrews SF, Ward AB. Yang YR, et al. Among authors: ward ab. bioRxiv [Preprint]. 2023 Aug 24:2023.08.23.554525. doi: 10.1101/2023.08.23.554525. bioRxiv. 2023. PMID: 37781590 Free PMC article. Updated. Preprint.
471 results