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MicroRNA-124 regulates osteoclast differentiation.
Lee Y, Kim HJ, Park CK, Kim YG, Lee HJ, Kim JY, Kim HH. Lee Y, et al. Among authors: lee hj. Bone. 2013 Oct;56(2):383-9. doi: 10.1016/j.bone.2013.07.007. Epub 2013 Jul 15. Bone. 2013. PMID: 23867221
Extracellular RNAs in periodontopathogenic outer membrane vesicles promote TNF-α production in human macrophages and cross the blood-brain barrier in mice.
Han EC, Choi SY, Lee Y, Park JW, Hong SH, Lee HJ. Han EC, et al. Among authors: lee y, lee hj. FASEB J. 2019 Dec;33(12):13412-13422. doi: 10.1096/fj.201901575R. Epub 2019 Sep 21. FASEB J. 2019. PMID: 31545910 Free PMC article.
The current study indicates that host gene regulation by microRNAs originating from OMVs of the periodontal pathogen Aa is a novel mechanism for host gene regulation and that the transfer of OMV exRNAs to the brain may cause neuroinflammatory diseases like Alzheimer's.-Han, E.-C. …
The current study indicates that host gene regulation by microRNAs originating from OMVs of the periodontal pathogen Aa is a novel mechanism …
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