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Targeting complement C3a receptor resolves mitochondrial hyperfusion and subretinal microglial activation in progranulin-deficient frontotemporal dementia.
Tan LX, Oertel FC, Cheng A, Cobigo Y, Keihani A, Bennett DJ, Abdelhak A, Montes SC, Chapman M, Chen RY, Cordano C, Ward ME, Casaletto K, Kramer JH, Rosen HJ, Boxer A, Miller BL, Green AJ, Elahi FM, Lakkaraju A. Tan LX, et al. Among authors: chen ry. bioRxiv [Preprint]. 2024 Jun 1:2024.05.29.595206. doi: 10.1101/2024.05.29.595206. bioRxiv. 2024. PMID: 38854134 Free PMC article. Preprint.
Farnesyltransferase inhibitor lonafarnib suppresses respiratory syncytial virus infection by blocking conformational change of fusion glycoprotein.
Yang Q, Xue B, Liu F, Lu Y, Tang J, Yan M, Wu Q, Chen R, Zhou A, Liu L, Liu J, Qu C, Wu Q, Fu M, Zhong J, Dong J, Chen S, Wang F, Zhou Y, Zheng J, Peng W, Shang J, Chen X. Yang Q, et al. Among authors: chen r. Signal Transduct Target Ther. 2024 Jun 10;9(1):144. doi: 10.1038/s41392-024-01858-5. Signal Transduct Target Ther. 2024. PMID: 38853183
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