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Ultradian hydrocortisone replacement alters neuronal processing, emotional ambiguity, affect and fatigue in adrenal insufficiency: The PULSES trial.
Russell G, Kalafatakis K, Durant C, Marchant N, Thakrar J, Thirard R, King J, Bowles J, Upton T, Thai NJ, Brooks JCW, Wilson A, Phillips K, Ferguson S, Grabski M, Rogers CA, Lampros T, Wilson S, Harmer C, Munafo M, Lightman SL. Russell G, et al. Among authors: thakrar j. J Intern Med. 2024 Jan;295(1):51-67. doi: 10.1111/joim.13721. Epub 2023 Oct 19. J Intern Med. 2024. PMID: 37857352 Free PMC article. Clinical Trial.
Ultradian rhythmicity of plasma cortisol is necessary for normal emotional and cognitive responses in man.
Kalafatakis K, Russell GM, Harmer CJ, Munafo MR, Marchant N, Wilson A, Brooks JC, Durant C, Thakrar J, Murphy P, Thai NJ, Lightman SL. Kalafatakis K, et al. Among authors: thakrar j. Proc Natl Acad Sci U S A. 2018 Apr 24;115(17):E4091-E4100. doi: 10.1073/pnas.1714239115. Epub 2018 Apr 9. Proc Natl Acad Sci U S A. 2018. PMID: 29632168 Free PMC article. Clinical Trial.
Glucocorticoid ultradian rhythmicity differentially regulates mood and resting state networks in the human brain: A randomised controlled clinical trial.
Kalafatakis K, Russell GM, Ferguson SG, Grabski M, Harmer CJ, Munafò MR, Marchant N, Wilson A, Brooks JC, Thakrar J, Murphy P, Thai NJ, Lightman SL. Kalafatakis K, et al. Among authors: thakrar j. Psychoneuroendocrinology. 2021 Feb;124:105096. doi: 10.1016/j.psyneuen.2020.105096. Epub 2020 Dec 1. Psychoneuroendocrinology. 2021. PMID: 33296841 Free PMC article. Clinical Trial.
Transcriptional and cell type profiles of cortical brain regions showing ultradian cortisol rhythm dependent responses to emotional face stimulation.
Habets PC, Kalafatakis K, Dzyubachyk O, van der Werff SJA, Keo A, Thakrar J, Mahfouz A, Pereira AM, Russell GM, Lightman SL, Meijer OC. Habets PC, et al. Among authors: thakrar j. Neurobiol Stress. 2023 Jan 4;22:100514. doi: 10.1016/j.ynstr.2023.100514. eCollection 2023 Jan. Neurobiol Stress. 2023. PMID: 36660181 Free PMC article.
Higher dose corticosteroids in patients admitted to hospital with COVID-19 who are hypoxic but not requiring ventilatory support (RECOVERY): a randomised, controlled, open-label, platform trial.
RECOVERY Collaborative Group. Electronic address: recoverytrial@ndph.ox.ac.uk; RECOVERY Collaborative Group. RECOVERY Collaborative Group. Electronic address: recoverytrial@ndph.ox.ac.uk, et al. Lancet. 2023 May 6;401(10387):1499-1507. doi: 10.1016/S0140-6736(23)00510-X. Epub 2023 Apr 13. Lancet. 2023. PMID: 37060915 Free PMC article. Clinical Trial.
13 results