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Podocyte injury at young age causes premature senescence and worsens glomerular aging.
Veloso Pereira BM, Zeng Y, Maggiore JC, Schweickart RA, Eng DG, Kaverina N, McKinzie SR, Chang A, Loretz CJ, Thieme K, Hukriede NA, Pippin JW, Wessely O, Shankland SJ. Veloso Pereira BM, et al. Among authors: schweickart ra. Am J Physiol Renal Physiol. 2024 Jan 1;326(1):F120-F134. doi: 10.1152/ajprenal.00261.2023. Epub 2023 Oct 19. Am J Physiol Renal Physiol. 2024. PMID: 37855038
Inhibiting NLRP3 signaling in aging podocytes improves their life- and health-span.
Kaverina N, Schweickart RA, Chan GC, Maggiore JC, Eng DG, Zeng Y, McKinzie SR, Perry HS, Ali A, O'Connor C, Pereira BMV, Theberge AB, Vaughan JC, Loretz CJ, Chang A, Hukriede NA, Bitzer M, Pippin JW, Wessely O, Shankland SJ. Kaverina N, et al. Among authors: schweickart ra. Aging (Albany NY). 2023 Jul 23;15(14):6658-6689. doi: 10.18632/aging.204897. Epub 2023 Jul 23. Aging (Albany NY). 2023. PMID: 37487005 Free PMC article.