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Podocyte injury at young age causes premature senescence and worsens glomerular aging.
Am J Physiol Renal Physiol. 2024 Jan 1;326(1):F120-F134. doi: 10.1152/ajprenal.00261.2023. Epub 2023 Oct 19.
Am J Physiol Renal Physiol. 2024.
PMID: 37855038
Inhibiting NLRP3 signaling in aging podocytes improves their life- and health-span.
Kaverina N, Schweickart RA, Chan GC, Maggiore JC, Eng DG, Zeng Y, McKinzie SR, Perry HS, Ali A, O'Connor C, Pereira BMV, Theberge AB, Vaughan JC, Loretz CJ, Chang A, Hukriede NA, Bitzer M, Pippin JW, Wessely O, Shankland SJ.
Kaverina N, et al. Among authors: schweickart ra.
Aging (Albany NY). 2023 Jul 23;15(14):6658-6689. doi: 10.18632/aging.204897. Epub 2023 Jul 23.
Aging (Albany NY). 2023.
PMID: 37487005
Free PMC article.
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Podocytes from hypertensive and obese mice acquire an inflammatory, senescent, and aged phenotype.
McKinzie SR, Kaverina N, Schweickart RA, Chaney CP, Eng DG, Pereira BMV, Kestenbaum B, Pippin JW, Wessely O, Shankland SJ.
McKinzie SR, et al. Among authors: schweickart ra.
Am J Physiol Renal Physiol. 2024 Apr 1;326(4):F644-F660. doi: 10.1152/ajprenal.00417.2023. Epub 2024 Feb 29.
Am J Physiol Renal Physiol. 2024.
PMID: 38420674
Free article.
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The epithelial polarity genes frazzled and GUK-holder adjust morphogen gradients to coordinate changes in cell position with cell fate specification.
Xue Y, Krishnan A, Chahda JS, Schweickart RA, Sousa-Neves R, Mizutani CM.
Xue Y, et al. Among authors: schweickart ra.
PLoS Biol. 2023 Mar 13;21(3):e3002021. doi: 10.1371/journal.pbio.3002021. eCollection 2023 Mar.
PLoS Biol. 2023.
PMID: 36913435
Free PMC article.
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