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Podocyte injury at young age causes premature senescence and worsens glomerular aging.
Am J Physiol Renal Physiol. 2024 Jan 1;326(1):F120-F134. doi: 10.1152/ajprenal.00261.2023. Epub 2023 Oct 19.
Am J Physiol Renal Physiol. 2024.
PMID: 37855038
Upregulated PD-1 signaling antagonizes glomerular health in aged kidneys and disease.
Pippin JW, Kaverina N, Wang Y, Eng DG, Zeng Y, Tran U, Loretz CJ, Chang A, Akilesh S, Poudel C, Perry HS, O'Connor C, Vaughan JC, Bitzer M, Wessely O, Shankland SJ.
Pippin JW, et al. Among authors: loretz cj.
J Clin Invest. 2022 Aug 15;132(16):e156250. doi: 10.1172/JCI156250.
J Clin Invest. 2022.
PMID: 35968783
Free PMC article.
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Inhibiting NLRP3 signaling in aging podocytes improves their life- and health-span.
Kaverina N, Schweickart RA, Chan GC, Maggiore JC, Eng DG, Zeng Y, McKinzie SR, Perry HS, Ali A, O'Connor C, Pereira BMV, Theberge AB, Vaughan JC, Loretz CJ, Chang A, Hukriede NA, Bitzer M, Pippin JW, Wessely O, Shankland SJ.
Kaverina N, et al. Among authors: loretz cj.
Aging (Albany NY). 2023 Jul 23;15(14):6658-6689. doi: 10.18632/aging.204897. Epub 2023 Jul 23.
Aging (Albany NY). 2023.
PMID: 37487005
Free PMC article.
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Global transcriptomic changes occur in aged mouse podocytes.
Wang Y, Eng DG, Kaverina NV, Loretz CJ, Koirala A, Akilesh S, Pippin JW, Shankland SJ.
Wang Y, et al. Among authors: loretz cj.
Kidney Int. 2020 Nov;98(5):1160-1173. doi: 10.1016/j.kint.2020.05.052. Epub 2020 Jun 25.
Kidney Int. 2020.
PMID: 32592814
Free PMC article.
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Snapshot of a large dynamic replicon in a halophilic archaeon: megaplasmid or minichromosome?
Ng WV, Ciufo SA, Smith TM, Bumgarner RE, Baskin D, Faust J, Hall B, Loretz C, Seto J, Slagel J, Hood L, DasSarma S.
Ng WV, et al.
Genome Res. 1998 Nov;8(11):1131-41. doi: 10.1101/gr.8.11.1131.
Genome Res. 1998.
PMID: 9847077
Free article.
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