Lai L - Search Results

1

Modeling SHANK3-associated autism spectrum disorder in Beagle dogs via CRISPR/Cas9 gene editing.

Tian R, Li Y, Zhao H, Lyu W, Zhao J, Wang X, Lu H, Xu H, Ren W, Tan QQ, Shi Q, Wang GD, Zhang YP, Lai L, Mi J, Jiang YH, Zhang YQ. Tian R, et al. Among authors: lai l. Mol Psychiatry. 2023 Sep;28(9):3739-3750. doi: 10.1038/s41380-023-02276-9. Epub 2023 Oct 17. Mol Psychiatry. 2023. PMID: 37848710

2

CRISPR/Cas9 facilitates investigation of neural circuit disease using human iPSCs: mechanism of epilepsy caused by an SCN1A loss-of-function mutation.

Liu J, Gao C, Chen W, Ma W, Li X, Shi Y, Zhang H, Zhang L, Long Y, Xu H, Guo X, Deng S, Yan X, Yu D, Pan G, Chen Y, Lai L, Liao W, Li Z. Liu J, et al. Among authors: lai l. Transl Psychiatry. 2016 Jan 5;6(1):e703. doi: 10.1038/tp.2015.203. Transl Psychiatry. 2016. PMID: 26731440 Free PMC article.

3

Targeted mutagenesis in mice via an engineered AsCas12f1 system.

Fan P, Wang H, Zhao F, Zhang T, Li J, Sun X, Yu Y, Xiong H, Lai L, Sui T. Fan P, et al. Among authors: lai l. Cell Mol Life Sci. 2024 Jan 28;81(1):63. doi: 10.1007/s00018-023-05100-3. Cell Mol Life Sci. 2024. PMID: 38280977 Free PMC article.

4

Exonuclease editor promotes precision of gene editing in mammalian cells.

Shi H, Li L, Mu S, Gou S, Liu X, Chen F, Chen M, Jin Q, Lai L, Wang K. Shi H, et al. Among authors: lai l. BMC Biol. 2024 May 20;22(1):119. doi: 10.1186/s12915-024-01918-w. BMC Biol. 2024. PMID: 38769511 Free PMC article.

5

Genome editing in large animals: current status and future prospects.

Zhao J, Lai L, Ji W, Zhou Q. Zhao J, et al. Among authors: lai l. Natl Sci Rev. 2019 May;6(3):402-420. doi: 10.1093/nsr/nwz013. Epub 2019 Jan 31. Natl Sci Rev. 2019. PMID: 34691891 Free PMC article.

6

Generation of a homozygous GRIN2A gene knockout human embryonic stem cell line using CRISPR/Cas9 system.

Luo X, Yang K, Jiang M, Chen T, Chi Y, Ma B, Lai L, Zou Q. Luo X, et al. Among authors: lai l. Stem Cell Res. 2023 Jun;69:103121. doi: 10.1016/j.scr.2023.103121. Epub 2023 May 9. Stem Cell Res. 2023. PMID: 37182381 Free article.

7

Generation of a homozygous RANGRF knockout hiPSC line by CRISPR/Cas9 system.

Jiang M, Tang C, Luo X, Zhou X, Chen M, Chi Y, Lai L, Zou Q. Jiang M, et al. Among authors: lai l. Stem Cell Res. 2023 Sep;71:103136. doi: 10.1016/j.scr.2023.103136. Epub 2023 Jun 7. Stem Cell Res. 2023. PMID: 37327621 Free article.

8

Evaluation of guide-free Cas9-induced genomic damage and transcriptome changes in pig embryos.

Ge W, Zhao X, Gou S, Jin Q, Chen F, Ouyang Z, Lai C, Cui T, Mai B, Lu S, Zhong K, Liang Y, Chen T, Wu H, Li N, Ye Y, Lai L, Wang K. Ge W, et al. Among authors: lai c, lai l. Mol Ther Nucleic Acids. 2023 Sep 20;34:102035. doi: 10.1016/j.omtn.2023.102035. eCollection 2023 Dec 12. Mol Ther Nucleic Acids. 2023. PMID: 37808924 Free PMC article.

9

Circular RNA profile in liver tissue of EpCAM knockout mice.

Yang Y, Liu S, Lei Z, Chen G, Huang L, Yang F, Lei Y, Liu Y, Yang L, Liu W, Lai L, Guo J. Yang Y, et al. Among authors: lai l. Int J Mol Med. 2019 Sep;44(3):1063-1077. doi: 10.3892/ijmm.2019.4270. Epub 2019 Jul 8. Int J Mol Med. 2019. PMID: 31524221 Free PMC article.

10

Genome-Wide CRISPR/Cas9 Screen Reveals a Role for SLC35A1 in the Adsorption of Porcine Deltacoronavirus.

Wang X, Jin Q, Xiao W, Fang P, Lai L, Xiao S, Wang K, Fang L. Wang X, et al. Among authors: lai l. J Virol. 2022 Dec 21;96(24):e0162622. doi: 10.1128/jvi.01626-22. Epub 2022 Dec 1. J Virol. 2022. PMID: 36453883 Free PMC article.

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