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The safety and efficacy of total mesorectal excision (TME) surgery following dose-escalation: Surgical outcomes from the organ preservation in early rectal adenocarcinoma (OPERA) trial, a European multicentre phase 3 randomised trial (NCT02505750).
Sun Myint A, Rao C, Barbet N, Thamphya B, Pace-Loscos T, Schiappa R, Magné N, Martel-Lafay I, Mineur L, Deberne M, Zilli T, Dhadda A, Gerard JP. Sun Myint A, et al. Among authors: dhadda a. Colorectal Dis. 2023 Nov;25(11):2160-2169. doi: 10.1111/codi.16773. Epub 2023 Oct 13. Colorectal Dis. 2023. PMID: 37837240 Clinical Trial.
Neoadjuvant chemoradiotherapy with radiation dose escalation with contact x-ray brachytherapy boost or external beam radiotherapy boost for organ preservation in early cT2-cT3 rectal adenocarcinoma (OPERA): a phase 3, randomised controlled trial.
Gerard JP, Barbet N, Schiappa R, Magné N, Martel I, Mineur L, Deberne M, Zilli T, Dhadda A, Myint AS; ICONE group. Gerard JP, et al. Among authors: dhadda a. Lancet Gastroenterol Hepatol. 2023 Apr;8(4):356-367. doi: 10.1016/S2468-1253(22)00392-2. Epub 2023 Feb 16. Lancet Gastroenterol Hepatol. 2023. PMID: 36801007 Clinical Trial.
Planned organ preservation for elderly patients with rectal cancer using short course radiotherapy and a contact brachytherapy boost-an International multi-institution analysis.
Steinke J, Jordan C, Rossides S, Minnaar H, Yu J, Franklin A, Rockall T, Dhadda AS, Andrew Hunter I, Mills J, Chadwick E, Silverman R, Folkesson J, Radu C, Myint AS, Stewart AJ. Steinke J, et al. Among authors: dhadda as. Clin Transl Radiat Oncol. 2023 Jan 11;39:100580. doi: 10.1016/j.ctro.2023.100580. eCollection 2023 Mar. Clin Transl Radiat Oncol. 2023. PMID: 36686563 Free PMC article.
6 versus 12 months of adjuvant trastuzumab for HER2-positive early breast cancer (PERSEPHONE): 4-year disease-free survival results of a randomised phase 3 non-inferiority trial.
Earl HM, Hiller L, Vallier AL, Loi S, McAdam K, Hughes-Davies L, Harnett AN, Ah-See ML, Simcock R, Rea D, Raj S, Woodings P, Harries M, Howe D, Raynes K, Higgins HB, Wilcox M, Plummer C, Mansi J, Gounaris I, Mahler-Araujo B, Provenzano E, Chhabra A, Abraham JE, Caldas C, Hall PS, McCabe C, Hulme C, Miles D, Wardley AM, Cameron DA, Dunn JA; PERSEPHONE Steering Committee and Trial Investigators. Earl HM, et al. Lancet. 2019 Jun 29;393(10191):2599-2612. doi: 10.1016/S0140-6736(19)30650-6. Epub 2019 Jun 6. Lancet. 2019. PMID: 31178152 Free PMC article. Clinical Trial.
Four consecutive yearly point-prevalence studies in Wales indicate lack of improvement in sepsis care on the wards.
Kopczynska M, Unwin H, Pugh RJ, Sharif B, Chandy T, Davies DJ, Shield ME, Purchase DE, Tilley SC, Poacher A, Oliva L, Willis S, Ray IE, Hui JNC, Payne BC, Wardle EF, Andrew F, Chan HMP, Barrington J, Hale J, Hawkins J, Nicholas JK, Wirt LE, Thomas LH, Walker M, Pan MP, Ray T, Asim UH, Maidman V, Atiyah Z, Nasser ZM, Tan ZX, Tan LJP, Szakmany T; Welsh Digital Data Collection Platform collaborators. Kopczynska M, et al. Sci Rep. 2021 Aug 10;11(1):16222. doi: 10.1038/s41598-021-95648-6. Sci Rep. 2021. PMID: 34376757 Free PMC article.
Effect of Celecoxib vs Placebo as Adjuvant Therapy on Disease-Free Survival Among Patients With Breast Cancer: The REACT Randomized Clinical Trial.
Coombes RC, Tovey H, Kilburn L, Mansi J, Palmieri C, Bartlett J, Hicks J, Makris A, Evans A, Loibl S, Denkert C, Murray E, Grieve R, Coleman R, Borley A, Schmidt M, Rautenberg B, Kunze CA, Rhein U, Mehta K, Mousa K, Dibble T, Lu XL, von Minckwitz G, Bliss JM; Randomized European Celecoxib Trial (REACT) Trial Management Group and Investigators. Coombes RC, et al. JAMA Oncol. 2021 Sep 1;7(9):1291-1301. doi: 10.1001/jamaoncol.2021.2193. JAMA Oncol. 2021. PMID: 34264305 Free PMC article. Clinical Trial.
43 results