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Deleting titin's I-band/A-band junction reveals critical roles for titin in biomechanical sensing and cardiac function.
Granzier HL, Hutchinson KR, Tonino P, Methawasin M, Li FW, Slater RE, Bull MM, Saripalli C, Pappas CT, Gregorio CC, Smith JE 3rd. Granzier HL, et al. Among authors: tonino p. Proc Natl Acad Sci U S A. 2014 Oct 7;111(40):14589-94. doi: 10.1073/pnas.1411493111. Epub 2014 Sep 22. Proc Natl Acad Sci U S A. 2014. PMID: 25246556 Free PMC article.
Triggering typical nemaline myopathy with compound heterozygous nebulin mutations reveals myofilament structural changes as pathomechanism.
Lindqvist J, Ma W, Li F, Hernandez Y, Kolb J, Kiss B, Tonino P, van der Pijl R, Karimi E, Gong H, Strom J, Hourani Z, Smith JE 3rd, Ottenheijm C, Irving T, Granzier H. Lindqvist J, et al. Among authors: tonino p. Nat Commun. 2020 Jun 1;11(1):2699. doi: 10.1038/s41467-020-16526-9. Nat Commun. 2020. PMID: 32483185 Free PMC article.
196 results