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Prednisolone and rapamycin reduce the plasma cell gene signature and may improve AAV gene therapy in cynomolgus macaques.
Kistner A, Chichester JA, Wang L, Calcedo R, Greig JA, Cardwell LN, Wright MC, Couthouis J, Sethi S, McIntosh BE, McKeever K, Wadsworth S, Wilson JM, Kakkis E, Sullivan BA. Kistner A, et al. Among authors: mcintosh be. Gene Ther. 2024 Mar;31(3-4):128-143. doi: 10.1038/s41434-023-00423-z. Epub 2023 Oct 13. Gene Ther. 2024. PMID: 37833563 Free PMC article.
Automated minute scale RNA-seq of pluripotent stem cell differentiation reveals early divergence of human and mouse gene expression kinetics.
Barry C, Schmitz MT, Argus C, Bolin JM, Probasco MD, Leng N, Duffin BM, Steill J, Swanson S, McIntosh BE, Stewart R, Kendziorski C, Thomson JA, Bacher R. Barry C, et al. Among authors: mcintosh be. PLoS Comput Biol. 2019 Dec 9;15(12):e1007543. doi: 10.1371/journal.pcbi.1007543. eCollection 2019 Dec. PLoS Comput Biol. 2019. PMID: 31815944 Free PMC article.
A Human Pluripotent Stem Cell-Based Screen for Smooth Muscle Cell Differentiation and Maturation Identifies Inhibitors of Intimal Hyperplasia.
Zhang J, McIntosh BE, Wang B, Brown ME, Probasco MD, Webster S, Duffin B, Zhou Y, Guo LW, Burlingham WJ, Kent C, Ferris M, Thomson JA. Zhang J, et al. Among authors: mcintosh be. Stem Cell Reports. 2019 Jun 11;12(6):1269-1281. doi: 10.1016/j.stemcr.2019.04.013. Epub 2019 May 9. Stem Cell Reports. 2019. PMID: 31080110 Free PMC article.
A Humanized Mouse Model Generated Using Surplus Neonatal Tissue.
Brown ME, Zhou Y, McIntosh BE, Norman IG, Lou HE, Biermann M, Sullivan JA, Kamp TJ, Thomson JA, Anagnostopoulos PV, Burlingham WJ. Brown ME, et al. Among authors: mcintosh be. Stem Cell Reports. 2018 Apr 10;10(4):1175-1183. doi: 10.1016/j.stemcr.2018.02.011. Epub 2018 Mar 22. Stem Cell Reports. 2018. PMID: 29576539 Free PMC article.
Uniform neural tissue models produced on synthetic hydrogels using standard culture techniques.
Barry C, Schmitz MT, Propson NE, Hou Z, Zhang J, Nguyen BK, Bolin JM, Jiang P, McIntosh BE, Probasco MD, Swanson S, Stewart R, Thomson JA, Schwartz MP, Murphy WL. Barry C, et al. Among authors: mcintosh be. Exp Biol Med (Maywood). 2017 Nov;242(17):1679-1689. doi: 10.1177/1535370217715028. Epub 2017 Jun 9. Exp Biol Med (Maywood). 2017. PMID: 28599598 Free PMC article.
Species-specific developmental timing is maintained by pluripotent stem cells ex utero.
Barry C, Schmitz MT, Jiang P, Schwartz MP, Duffin BM, Swanson S, Bacher R, Bolin JM, Elwell AL, McIntosh BE, Stewart R, Thomson JA. Barry C, et al. Among authors: mcintosh be. Dev Biol. 2017 Mar 15;423(2):101-110. doi: 10.1016/j.ydbio.2017.02.002. Epub 2017 Feb 6. Dev Biol. 2017. PMID: 28179190 Free PMC article.
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