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PPTC7 maintains mitochondrial protein content by suppressing receptor-mediated mitophagy.
Niemi NM, Serrano LR, Muehlbauer LK, Balnis CE, Wei L, Smith AJ, Kozul KL, Forny M, Connor OM, Rashan EH, Shishkova E, Schueler KL, Keller MP, Attie AD, Friedman JR, Pagan JK, Coon JJ, Pagliarini DJ. Niemi NM, et al. Among authors: pagan jk. Nat Commun. 2023 Oct 13;14(1):6431. doi: 10.1038/s41467-023-42069-w. Nat Commun. 2023. PMID: 37833277 Free PMC article.
FBXL4 suppresses mitophagy by restricting the accumulation of NIX and BNIP3 mitophagy receptors.
Nguyen-Dien GT, Kozul KL, Cui Y, Townsend B, Kulkarni PG, Ooi SS, Marzio A, Carrodus N, Zuryn S, Pagano M, Parton RG, Lazarou M, Millard SS, Taylor RW, Collins BM, Jones MJ, Pagan JK. Nguyen-Dien GT, et al. Among authors: pagan jk. EMBO J. 2023 Jul 3;42(13):e112767. doi: 10.15252/embj.2022112767. Epub 2023 May 10. EMBO J. 2023. PMID: 37161784 Free PMC article.
Centrosome Reduction Promotes Terminal Differentiation of Human Cardiomyocytes.
Ng DCH, Richards DK, Mills RJ, Ho UY, Perks HL, Tucker CR, Voges HK, Pagan JK, Hudson JE. Ng DCH, et al. Among authors: pagan jk. Stem Cell Reports. 2020 Oct 13;15(4):817-826. doi: 10.1016/j.stemcr.2020.08.007. Epub 2020 Sep 17. Stem Cell Reports. 2020. PMID: 32946803 Free PMC article.
FEM1 proteins are ancient regulators of SLBP degradation.
Dankert JF, Pagan JK, Starostina NG, Kipreos ET, Pagano M. Dankert JF, et al. Among authors: pagan jk. Cell Cycle. 2017 Mar 19;16(6):556-564. doi: 10.1080/15384101.2017.1284715. Epub 2017 Jan 24. Cell Cycle. 2017. PMID: 28118078 Free PMC article.
SCF ubiquitin ligase-targeted therapies.
Skaar JR, Pagan JK, Pagano M. Skaar JR, et al. Among authors: pagan jk. Nat Rev Drug Discov. 2014 Dec;13(12):889-903. doi: 10.1038/nrd4432. Epub 2014 Nov 14. Nat Rev Drug Discov. 2014. PMID: 25394868 Free PMC article. Review.
17 results