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Deficiency of terminal ADP-ribose protein glycohydrolase TARG1/C6orf130 in neurodegenerative disease.
Sharifi R, Morra R, Appel CD, Tallis M, Chioza B, Jankevicius G, Simpson MA, Matic I, Ozkan E, Golia B, Schellenberg MJ, Weston R, Williams JG, Rossi MN, Galehdari H, Krahn J, Wan A, Trembath RC, Crosby AH, Ahel D, Hay R, Ladurner AG, Timinszky G, Williams RS, Ahel I. Sharifi R, et al. Among authors: williams rs, williams jg. EMBO J. 2013 May 2;32(9):1225-37. doi: 10.1038/emboj.2013.51. Epub 2013 Mar 12. EMBO J. 2013. PMID: 23481255 Free PMC article.
Reversal of DNA damage induced Topoisomerase 2 DNA-protein crosslinks by Tdp2.
Schellenberg MJ, Perera L, Strom CN, Waters CA, Monian B, Appel CD, Vilas CK, Williams JG, Ramsden DA, Williams RS. Schellenberg MJ, et al. Among authors: williams rs, williams jg. Nucleic Acids Res. 2016 May 5;44(8):3829-44. doi: 10.1093/nar/gkw228. Epub 2016 Apr 8. Nucleic Acids Res. 2016. PMID: 27060144 Free PMC article.
Grc3 programs the essential endoribonuclease Las1 for specific RNA cleavage.
Pillon MC, Sobhany M, Borgnia MJ, Williams JG, Stanley RE. Pillon MC, et al. Among authors: williams jg. Proc Natl Acad Sci U S A. 2017 Jul 11;114(28):E5530-E5538. doi: 10.1073/pnas.1703133114. Epub 2017 Jun 26. Proc Natl Acad Sci U S A. 2017. PMID: 28652339 Free PMC article.
ZATT (ZNF451)-mediated resolution of topoisomerase 2 DNA-protein cross-links.
Schellenberg MJ, Lieberman JA, Herrero-Ruiz A, Butler LR, Williams JG, Muñoz-Cabello AM, Mueller GA, London RE, Cortés-Ledesma F, Williams RS. Schellenberg MJ, et al. Among authors: williams rs, williams jg. Science. 2017 Sep 29;357(6358):1412-1416. doi: 10.1126/science.aam6468. Epub 2017 Sep 14. Science. 2017. PMID: 28912134 Free PMC article.
Cryo-EM Structures of the SARS-CoV-2 Endoribonuclease Nsp15.
Pillon MC, Frazier MN, Dillard LB, Williams JG, Kocaman S, Krahn JM, Perera L, Hayne CK, Gordon J, Stewart ZD, Sobhany M, Deterding LJ, Hsu AL, Dandey VP, Borgnia MJ, Stanley RE. Pillon MC, et al. Among authors: williams jg. bioRxiv [Preprint]. 2020 Aug 11:2020.08.11.244863. doi: 10.1101/2020.08.11.244863. bioRxiv. 2020. PMID: 32803198 Free PMC article. Updated. Preprint.
Cryo-EM structures of the SARS-CoV-2 endoribonuclease Nsp15 reveal insight into nuclease specificity and dynamics.
Pillon MC, Frazier MN, Dillard LB, Williams JG, Kocaman S, Krahn JM, Perera L, Hayne CK, Gordon J, Stewart ZD, Sobhany M, Deterding LJ, Hsu AL, Dandey VP, Borgnia MJ, Stanley RE. Pillon MC, et al. Among authors: williams jg. Nat Commun. 2021 Jan 27;12(1):636. doi: 10.1038/s41467-020-20608-z. Nat Commun. 2021. PMID: 33504779 Free PMC article.
Characterization of SARS2 Nsp15 nuclease activity reveals it's mad about U.
Frazier MN, Dillard LB, Krahn JM, Perera L, Williams JG, Wilson IM, Stewart ZD, Pillon MC, Deterding LJ, Borgnia MJ, Stanley RE. Frazier MN, et al. Among authors: williams jg. Nucleic Acids Res. 2021 Sep 27;49(17):10136-10149. doi: 10.1093/nar/gkab719. Nucleic Acids Res. 2021. PMID: 34403466 Free PMC article.
710 results