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Cryptic MHC-E epitope from influenza elicits a potent cytolytic T cell response.
Hogan MJ, Maheshwari N, Begg BE, Nicastri A, Hedgepeth EJ, Muramatsu H, Pardi N, Miller MA, Reilly SP, Brossay L, Lynch KW, Ternette N, Eisenlohr LC. Hogan MJ, et al. Among authors: lynch kw. Nat Immunol. 2023 Nov;24(11):1933-1946. doi: 10.1038/s41590-023-01644-5. Epub 2023 Oct 12. Nat Immunol. 2023. PMID: 37828378
Nuclear speckle integrity and function require TAO2 kinase.
Gao S, Esparza M, Dehghan I, Aksenova V, Zhang K, Batten K, Ferretti MB, Begg BE, Cagatay T, Shay JW, García-Sastre A, Goldsmith EJ, Chen ZJ, Dasso M, Lynch KW, Cobb MH, Fontoura BMA. Gao S, et al. Among authors: lynch kw. Proc Natl Acad Sci U S A. 2022 Jun 21;119(25):e2206046119. doi: 10.1073/pnas.2206046119. Epub 2022 Jun 15. Proc Natl Acad Sci U S A. 2022. PMID: 35704758 Free PMC article.
Co-regulatory activity of hnRNP K and NS1-BP in influenza and human mRNA splicing.
Thompson MG, Muñoz-Moreno R, Bhat P, Roytenberg R, Lindberg J, Gazzara MR, Mallory MJ, Zhang K, García-Sastre A, Fontoura BMA, Lynch KW. Thompson MG, et al. Among authors: lynch kw. Nat Commun. 2018 Jun 19;9(1):2407. doi: 10.1038/s41467-018-04779-4. Nat Commun. 2018. PMID: 29921878 Free PMC article.
Pharmacological activation of STING blocks SARS-CoV-2 infection.
Li M, Ferretti M, Ying B, Descamps H, Lee E, Dittmar M, Lee JS, Whig K, Kamalia B, Dohnalová L, Uhr G, Zarkoob H, Chen YC, Ramage H, Ferrer M, Lynch K, Schultz DC, Thaiss CA, Diamond MS, Cherry S. Li M, et al. Sci Immunol. 2021 May 18;6(59):eabi9007. doi: 10.1126/sciimmunol.abi9007. Sci Immunol. 2021. PMID: 34010142 Free PMC article.
Influenza virus mRNA trafficking through host nuclear speckles.
Mor A, White A, Zhang K, Thompson M, Esparza M, Muñoz-Moreno R, Koide K, Lynch KW, García-Sastre A, Fontoura BM. Mor A, et al. Among authors: lynch kw. Nat Microbiol. 2016 May 27;1(7):16069. doi: 10.1038/nmicrobiol.2016.69. Nat Microbiol. 2016. PMID: 27572970 Free PMC article.
Influenza virus mRNAs encode determinants for nuclear export via the cellular TREX-2 complex.
Bhat P, Aksenova V, Gazzara M, Rex EA, Aslam S, Haddad C, Gao S, Esparza M, Cagatay T, Batten K, El Zahed SS, Arnaoutov A, Zhong H, Shay JW, Tolbert BS, Dasso M, Lynch KW, García-Sastre A, Fontoura BMA. Bhat P, et al. Among authors: lynch kw. Nat Commun. 2023 Apr 21;14(1):2304. doi: 10.1038/s41467-023-37911-0. Nat Commun. 2023. PMID: 37085480 Free PMC article.
90 results