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Mis-spliced transcripts generate de novo proteins in TDP-43-related ALS/FTD.
Seddighi S, Qi YA, Brown AL, Wilkins OG, Bereda C, Belair C, Zhang YJ, Prudencio M, Keuss MJ, Khandeshi A, Pickles S, Kargbo-Hill SE, Hawrot J, Ramos DM, Yuan H, Roberts J, Sacramento EK, Shah SI, Nalls MA, Colón-Mercado JM, Reyes JF, Ryan VH, Nelson MP, Cook CN, Li Z, Screven L, Kwan JY, Mehta PR, Zanovello M, Hallegger M, Shantaraman A, Ping L, Koike Y, Oskarsson B, Staff NP, Duong DM, Ahmed A, Secrier M, Ule J, Jacobson S, Reich DS, Rohrer JD, Malaspina A, Dickson DW, Glass JD, Ori A, Seyfried NT, Maragkakis M, Petrucelli L, Fratta P, Ward ME. Seddighi S, et al. Among authors: ryan vh. Sci Transl Med. 2024 Feb 14;16(734):eadg7162. doi: 10.1126/scitranslmed.adg7162. Epub 2024 Feb 14. Sci Transl Med. 2024. PMID: 38277467
Improved accuracy and efficiency of primary care fall risk screening of older adults using a machine learning approach.
Song W, Latham NK, Liu L, Rice HE, Sainlaire M, Min L, Zhang L, Thai T, Kang MJ, Li S, Tejeda C, Lipsitz S, Samal L, Carroll DL, Adkison L, Herlihy L, Ryan V, Bates DW, Dykes PC. Song W, et al. Among authors: ryan v. J Am Geriatr Soc. 2024 Apr;72(4):1145-1154. doi: 10.1111/jgs.18776. Epub 2024 Jan 13. J Am Geriatr Soc. 2024. PMID: 38217355
VXX-401, a novel anti-PCSK9 vaccine, reduces LDL-C in cynomolgus monkeys.
Vroom MM, Lu H, Lewis M, Thibodeaux BA, Brooks JK, Longo MS, Ramos MM, Sahni J, Wiggins J, Boyd JD, Wang S, Ding S, Hellerstein M, Ryan V, Powchik P, Dodart JC. Vroom MM, et al. Among authors: ryan v. J Lipid Res. 2024 Feb;65(2):100497. doi: 10.1016/j.jlr.2024.100497. Epub 2024 Jan 10. J Lipid Res. 2024. PMID: 38216056 Free PMC article.
An ANXA11 P93S variant dysregulates TDP-43 and causes corticobasal syndrome.
Snyder A, Ryan VH, Hawrot J, Lawton S, Ramos DM, Qi YA, Johnson K, Reed X, Johnson NL, Kollasch AW, Duffy M, VandeVrede L, Cochran JN, Miller BL, Toro C, Bielekova B, Yokoyama JS, Marks DS, Kwan JY, Cookson MR, Ward ME. Snyder A, et al. Among authors: ryan vh. Res Sq [Preprint]. 2023 Oct 19:rs.3.rs-3462973. doi: 10.21203/rs.3.rs-3462973/v1. Res Sq. 2023. PMID: 37886540 Free PMC article. Preprint.
Associations between PM2.5 and O3 exposures and new onset type 2 diabetes in regional and national samples in the United States.
McAlexander TP, Ryan V, Uddin J, Kanchi R, Thorpe L, Schwartz BS, Carson A, Rolka DB, Adhikari S, Pollak J, Lopez P, Smith M, Meeker M, McClure LA. McAlexander TP, et al. Among authors: ryan v. Environ Res. 2023 Dec 15;239(Pt 1):117248. doi: 10.1016/j.envres.2023.117248. Epub 2023 Oct 10. Environ Res. 2023. PMID: 37827369 Free article.
144 results